Extended Pleurectomy and Decortication for Malignant Pleural Mesothelioma Is an Effective and Safe Cytoreductive Surgery in the Elderly

The Annals of Thoracic Surgery
Trevor WilliamsWickii T Vigneswaran

Abstract

A survival advantage has been observed among patients with malignant pleural mesothelioma undergoing maximal cytoreductive surgery and adjuvant therapy. Elderly patients are considered higher risk for these radical operations and are commonly not offered surgical treatment. We reviewed our experience with extended pleurectomy and decortication among patients 70 years or older and compared them with a cohort of younger patients undergoing extended pleurectomy and decortication for malignant pleural mesothelioma. We performed a retrospective review of 117 consecutive patients undergoing extended pleurectomy and decortication at a university hospital from January 2008 to December 2013. Patients 70 years and older were compared with younger patients for postoperative outcome and survival. Survival was estimated using the Kaplan-Meier method. Fifty-four patients were 70 years or older; 63 were younger than 70 years. Older patients had more hypertension (71.2% versus 45.2%; p = 0.004) and coronary artery disease (22.6% versus 6.5%; p = 0.006). Major complications occurred in 3 patients (5.5%) in the older group and in 7 patients (11.1%) of the younger group (not significant). There were 2 deaths in each group after surgery (3.7% olde...Continue Reading

References

Jul 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicholas J VogelzangPaolo Paoletti
Sep 28, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Raja M FloresHarvey I Pass
Oct 27, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Michael T Milano, Hong Zhang
Aug 19, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·David RiceUNKNOWN International Association for the Study of Lung Cancer International Staging Committee and the International Mesothelioma In
Nov 2, 2011·The Lancet Oncology·Walter WederNico van Zandwijk
Aug 28, 2012·The Annals of Thoracic Surgery·Nathan M MollbergWickii T Vigneswaran
Oct 17, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Valerie W RuschUNKNOWN IASLC Staging Committee
Jun 19, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Christopher CaoTristan D Yan
Dec 24, 2013·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Christopher CaoTristan D Yan
Feb 13, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Pietro BovolatoUgo Pastorino
Apr 15, 2014·The Journal of Thoracic and Cardiovascular Surgery·Bryan M BurtWickii T Vigneswaran

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Citations

Mar 26, 2016·Expert Review of Respiratory Medicine·Pietro Bertoglio, David A Waller
Nov 3, 2015·The Annals of Thoracic Surgery·Bryan M Burt
Oct 1, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·David RiceUNKNOWN Mesothelioma Domain of the IASLC Staging and Prognostic Factors Committee, advisory boards and participating institutions
Oct 10, 2019·Expert Review of Respiratory Medicine·Giovanni Luca Ceresoli, Antonio Rossi
Nov 10, 2017·Current Opinion in Anaesthesiology·Stephen J ShepherdGuillermo Martinez
Apr 19, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Giuseppe MarulliFederico Rea
Mar 25, 2019·Oncoimmunology·Pranav MurthyMichael T Lotze
Oct 20, 2017·Interactive Cardiovascular and Thoracic Surgery·Annabel Jane SharkeyDavid A Waller
Apr 24, 2019·Annals of Surgical Oncology·Vivek VermaCharles B Simone
May 25, 2021·General Thoracic and Cardiovascular Surgery·Fumihiro TanakaKoji Kuroda

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