PMID: 11343933May 10, 2001Paper

Extended thymectomy in myasthenia gravis: a team-work of neurologist, thoracic surgeon and anaesthesist may improve the outcome

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
A MussiC A Angeletti

Abstract

We reviewed our overall experience on 163 patients, affected by myasthenia gravis, who underwent thymectomy between 1976 and 1998. A comparison between the oldest series of 72 patients (January 1976-December 1992), referred by various neurologists and operated on through different approaches, and the last 91 patients (January 1993-December 1998), taking part in a strict diagnostic-therapeutical programme, was made. Anagraphic data, duration of symptoms, the surgical approach, necessity of respiratory assistance, the hospital stay, histopathological findings, preoperative and postoperative Osserman classification, as well as medications, were globally analyzed and then compared in the two groups. Significant differences in the length of hospitalization (8.7 days vs. 4.2 days; P=0.00001) and in the prolonged intubation rate (18 vs. 0; P<0.000001) were observed in the most recent series. Patients in the pre-operative Osserman stage I and operated on in the second period had a higher complete remission rate at the univariate analysis (P<0.001 and P<0.0001, respectively). At the multivariate analysis the only parameter which affected the outcome was to be operated on in the second period (P<0.01). Our experience confirms the role of...Continue Reading

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Citations

May 28, 2005·The Annals of Thoracic Surgery·Marco LucchiAlfredo Mussi
Mar 1, 2012·Interactive Cardiovascular and Thoracic Surgery·Marco LucchiUNKNOWN EACTS Thymic Working Group
Feb 15, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Giovanni LeuzziPierluigi Granone
Sep 6, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Zhenguang ChenHonghe Luo
Mar 29, 2014·The International Journal of Neuroscience·Giovanni LeuzziFrancesco Facciolo
Aug 12, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Zhifeng MaoMaree L Hackett
Mar 27, 2003·The Journal of Thoracic and Cardiovascular Surgery·Marco LucchiCarlo Alberto Angeletti
Oct 24, 2012·Journal of Clinical Neurology·Zhi-Feng MaoMaree L Hackett
Feb 22, 2008·Patient Safety in Surgery·Nikolaos BarbetakisChristodoulos Tsilikas
Nov 2, 2005·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·P C ChangM F Huang
Mar 11, 2020·Minerva ginecologica·Maria G PiccioniMarco Monti
Mar 15, 2020·Interactive Cardiovascular and Thoracic Surgery·Vittorio AprileMarco Lucchi

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