PMID: 11314157Apr 21, 2001Paper

Extending the boundaries of the Declaration of Helsinki: a case study of an unethical experiment in a non-medical setting

Journal of Medical Ethics
E D RichterZ Weinberger

Abstract

To examine the ethical issues involved in governmental decisions with potential health risks, we review the history of the decision to raise the interurban speed limit in Israel in light of its impact on road death and injury. In 1993, the Israeli Ministry of Transportation initiated an "experiment" to raise the interurban speed limit from 90 to 100 kph. The "experiment" did not include a protocol and did not specify cut-off points for early termination in the case of adverse results. After the raise in the speed limit, the death toll on interurban roads rose as a result of a sudden increase in speeds and case fatality rates. The committee's decision is a case study in unfettered human experimentation and public health risks when the setting is non-medical and lacks a defined ethical framework. The case study states the case for extending Helsinki type safeguards to experimentation in non-medical settings.

References

Oct 27, 1989·JAMA : the Journal of the American Medical Association·M M GallaherH F Hull
Dec 1, 1969·The Journal of Applied Psychology·F Schmidt, J Tiffin

❮ Previous
Next ❯

Citations

Nov 27, 2009·Science and Engineering Ethics·Sven Ove Hansson
Jun 24, 2004·International Journal of Occupational Medicine and Environmental Health·Elihu D Richter, Richard Laster
Aug 10, 2010·The American Journal of Bioethics : AJOB·Sven Ove Hansson
Mar 15, 2006·Annual Review of Public Health·Elihu D RichterGerald Ben-David
Apr 1, 2004·American Journal of Public Health·Elihu D RichterAbraham Israeli
Feb 28, 2015·Science and Engineering Ethics·Sven Ove Hansson
Sep 24, 2005·Theoretical Medicine and Bioethics·Nancy S Jecker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
Lee S FriedmanE D Richter
Archives of Environmental Health
E D Richter, T Berman
Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention
E D RichterT Berman
Theoretical Medicine and Bioethics
Sven Ove Hansson
© 2021 Meta ULC. All rights reserved