PMID: 11899193Mar 20, 2002Paper

Extending the usable size range of homografts in the pulmonary circulation: outcome of bicuspid homografts

The Annals of Thoracic Surgery
Bhagawan KoiralaWilliam G Williams

Abstract

Small-sized homografts are often not available, making the use of surgically reduced cryopreserved homograft conduits appealing. From January 1993 to January 2000, 21 large homografts were size-reduced by excising one leaflet and were implanted in the pulmonary circulation. Valve function was compared with 21 children-matched for weight, homograft size, and year of operation-who received a standard homograft. Implanted homograft size and patient weight were equivalent in both the bicuspid and standard groups. Median (range) in-hospital peak instantaneous echocardiographic gradient across the valve was 0 mm Hg (0 to 19) in the bicuspid group versus 0 mm Hg (0 to 17) in the standard group (p = 0.65). Median (range) in-hospital pulmonary insufficiency (scale of 0 to 4) was 2 (0 to 3) in the bicuspid group versus 1.5 (0 to 3) in the standard group (n = 10, p = 0.34). At a follow-up of 54+/-29 months there was no significant difference in conduit reinterventions between the groups. Surgical creation of a bicuspid valve in the pulmonary circulation results in a functionally equivalent conduit compared with standard homograft as measured by early and midterm valve function.

References

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Citations

Apr 26, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sander BramerAd J J C Bogers
Apr 28, 2006·Pediatric Research·Younes BoudjemlinePhilipp Bonhoeffer
Jan 8, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·David R Koolbergen
Jul 30, 2010·The Annals of Thoracic Surgery·Terry ShihRichard G Ohye
Feb 1, 2005·The Annals of Thoracic Surgery·Volkhard GöberThierry P Carrel
Jun 27, 2006·The Journal of Thoracic and Cardiovascular Surgery·David Michael McMullanChristian P Brizard
Oct 26, 2005·The Annals of Thoracic Surgery·Zarry TavakkolRichard G Ohye
Nov 29, 2015·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Julie CleuziouChristian Schreiber
Nov 19, 2005·Expert Review of Medical Devices·Thierry Carrel
Oct 14, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Katrien FrançoisThierry Bové

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