Extensive brainstem ischemia on neuroimaging does not preclude meaningful recovery from locked-in syndrome: two cases of endovascularly managed basilar thrombosis

Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Nestor D TomyczTudor G Jovin

Abstract

We report 2 patients with angiographically demonstrated basilar artery thrombosis who received emergent intra-arterial thrombolysis with successful recanalization of the basilar artery. In the ensuing weeks after the procedure, both patients were in a locked-in state and had sustained large bilateral regions of pontine ischemia on brain imaging. Following aggressive supportive care and rehabilitation, outcomes obtained prospectively revealed that both patients made a remarkable recovery, becoming fully independent with Barthel scores of 20 and modified Rankin scores of 2.

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Citations

Apr 24, 2009·AJNR. American Journal of Neuroradiology·R G NogueiraJ A Hirsch
Nov 26, 2009·Annals of Neurology·David S Liebeskind
Sep 19, 2012·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Alexander KeedyMax Wintermark
Aug 22, 2009·Stroke; a Journal of Cerebral Circulation·Archit Bhatt

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