PMID: 16515241Mar 7, 2006Paper

Extensive chronic graft-versus-host disease of skin successfully treated with thalidomide

The Journal of the Association of Physicians of India
V NairVibha Dutta

Abstract

Thirty years female underwent allogenic peripheral blood stem cell transplantation for chronic myeloid leukaemia--chronic phase. She developed grade II acute skin graft-versus-host disease (GVHD) which was treated with cyclosporine and a short course of steroids. She developed extensive chronic GVHD of the skin and liver three hundred days post-transplant. She was managed with the standard immunosuppressants with partial response of liver dysfunction but no response of skin lesions. She showed a good response to therapy with resolution of skin lesions after treatment with thalidomide.

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

São Paulo Medical Journal = Revista Paulista De Medicina
Daniela Máira CardozoJeane Eliete Laguila Visentainer
The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society
Xin JingSuzanne Meleg-Smith
The Netherlands Journal of Medicine
M H van de PoelH C Schouten
© 2021 Meta ULC. All rights reserved