PMID: 8604330Mar 15, 1996Paper

Extensive RNA editing of U to C in addition to C to U substitution in the rbcL transcripts of hornwort chloroplasts and the origin of RNA editing in green plants

Nucleic Acids Research
Koichi YoshinagaK Uedal

Abstract

We cloned and sequenced a portion of chloroplast DNA from the hornwort Anthoceros formosae. A nucleotide sequence of 7556 bp contained structures similar to those of ndhK, ndhC, trnV, trnM, atpE, atpB, rbcL, trnR and accD. The arrangement of these was the same as that of other chloroplast DNA. However, two nonsense codons were located within the putative coding region of rbcL, although they were used as putative termination codons of the genes. RNA was extensively edited in the transcripts of rbcL when cDNA sequences were analyzed. The unusual nonsense codons of TGA and TAA became CGA and CAA respectively. These are examples of U to C type RNA editing, which was never been found before in chloroplast mRNA. In general, 13 Cs of genomic DNA were found as Ts in the cDNA sequence and seven Ts were found as Cs. This is the first finding of RNA editing on the transcripts of rbcL and also in bryophytes. This event had been thought to arise in land plants after the split of bryophytes. The origin of RNA editing is discussed in relation to the landing of green plants.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Mar 15, 1990·Nature·S L Baldauf, J D Palmer
Dec 22, 1989·Science·R HieselA Brennicke
Oct 19, 1989·Nature·P S Covello, M W Gray
Mar 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·S RufH Kössel
Jun 1, 1994·Molecular Phylogenetics and Evolution·J R Manhart
Mar 24, 1994·Nature·D A MaslovL Simpson
Oct 1, 1993·The Plant Journal : for Cell and Molecular Biology·R FreyerH Kössel
Jan 18, 1994·Proceedings of the National Academy of Sciences of the United States of America·R HieselA Brennicke

❮ Previous
Next ❯

Citations

Jun 28, 2011·Current Genetics·Dominique BéguAlejandro Araya
Jul 20, 2002·Molecular Phylogenetics and Evolution·Mark P SimmonsJohn V Freudenstein
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·M W Gray
Jul 25, 2008·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Kei YuraMamoru Sugita
Apr 25, 2002·Nucleic Acids Research·Jaime VillegasLuis O Burzio
Apr 25, 2003·Nucleic Acids Research·Masanori KugitaKoichi Yoshinaga
Jul 9, 2004·Nucleic Acids Research·Andreas FiebigRalph Bock
Feb 3, 1999·Annual Review of Genetics·M SugiuraM Sugita
May 27, 1997·Proceedings of the National Academy of Sciences of the United States of America·T WakasugiM Sugiura
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·R FreyerH Kössel
Oct 13, 2010·Cellular and Molecular Life Sciences : CMLS·Volker Knoop
May 25, 2010·Plant Physiology and Biochemistry : PPB·Mercedes Martín, Bartolomé Sabater
Mar 9, 2010·New Biotechnology·Michael Tillich, Kirsten Krause
Jan 30, 2014·The Plant Journal : for Cell and Molecular Biology·Yusuke YagiIan Small
Nov 28, 2000·Annual Review of Genetics·J M Gott, R B Emeson
Dec 20, 2017·Genes·Tapan Kumar MohantaHanhong Bae
Oct 1, 2004·American Journal of Botany·Jonathan Shaw, Karen Renzaglia
May 1, 2006·American Journal of Botany·Juan Carlos Villarreal A, Karen Sue Renzaglia
Sep 24, 2005·Journal of Molecular Evolution·R Joel Duff, Francisco B-G Moore

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.