Extent of resection in the management of duodenal adenocarcinoma

American Journal of Surgery
I G KaklamanosA S Livingstone

Abstract

It has been postulated that segmental duodenal resection (SR) is not an adequate operation for patients with adenocarcinoma of the duodenum and that pancreaticoduodenectomy (PD) is the procedure of choice, regardless of the tumor site. However, data from previous studies do not clearly support this position. We reviewed the records of 63 patients treated for duodenal adenocarcinoma from 1979 through 1998. Perioperative outcome, patient survival, and extent of lymphadenectomy were compared in patients who underwent PD and SR. The overall morbidity for PD and SR was 27% and 18%, respectively (not significant [NS]). Patients who underwent SR had a 5-year survival of 60% versus 30% for patients who underwent PD (NS). Lymph node status was a prognostic factor for survival (P = 0.014). The mean number of lymph nodes in the specimens was 9.9 +/- 2.1 for PD and 8.3 +/- 4.4 for SR (NS). Segmental duodenal resection for patients with duodenal adenocarcinoma is associated with acceptable postoperative morbidity and long-term survival. The procedure is especially well suited for distal duodenal tumors. Clearance of lymph nodes and outcome are comparable to PD.

References

Oct 1, 1988·World Journal of Surgery·E C LaiR K Tompkins
Feb 1, 1981·American Journal of Surgery·D R JoestingL H Weiland
Oct 1, 1994·The British Journal of Surgery·D M Scott-Coombes, R C Williamson
Dec 1, 1993·American Journal of Surgery·R DelcoreA S Hermreck

❮ Previous
Next ❯

Citations

Feb 22, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Edwin O OnkendiFlorencia G Que
Apr 29, 2009·Journal of Gastrointestinal Cancer·Shao-Liang HanSheng-Hong Lan
Jun 11, 2009·Journal of Gastrointestinal Cancer·Shao-liang HanSheng-Hong Lan
May 1, 2010·Journal of Gastrointestinal Cancer·Shao-Liang HanSheng-Hong Lan
Jun 26, 2009·Journal de chirurgie·K SlimP Valleur
Jul 31, 2013·Nature Reviews. Clinical Oncology·Kanwal Raghav, Michael J Overman
Jul 14, 2001·ANZ Journal of Surgery·R R HutchinsS J Snooks
Jan 1, 2012·Journal of Surgical Case Reports·D LamR Hernandez-Alejandro
Sep 21, 2010·BMC Gastroenterology·Peter T KalogerinisAlexandros G Georgakilas
Apr 27, 2013·Journal of Medical Case Reports·Oguz KocEsra Pasaoglu
Dec 15, 2011·Annals of Surgical Oncology·George A PoultsidesRichard D Schulick
Mar 25, 2010·World Journal of Gastroenterology : WJG·Shao-Liang HanPeng-Fei Wang
Jan 29, 2014·Japanese Journal of Clinical Oncology·Yuichiro KatoMasaru Konishi
Mar 19, 2014·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Ian ReynoldsDeborah A Mcnamara
Oct 24, 2014·Journal of Gastrointestinal Cancer·Santosh Shenoy
Aug 28, 2014·Annals of Surgical Oncology·Jordan M CloydGeorge A Poultsides
Feb 16, 2006·World Journal of Surgery·Ting-Jung WuMiin-Fu Chen
Sep 9, 2011·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·W SendtA Altendorf-Hofmann
Nov 20, 2012·Journal of the Chinese Medical Association : JCMA·Tsung-Jung LiangKing-Tong Mok
Jun 12, 2010·Gastroentérologie Clinique Et Biologique·A ZaananT Aparicio
May 10, 2013·ANZ Journal of Surgery·Sang Yeup LeeYoung-Joo Lee
Mar 18, 2015·The British Journal of Surgery·L SolainiUNKNOWN UK Duodenal Cancer Study Group
May 8, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Stéphane BourgouinYves-Patrice Le Treut
Apr 29, 2015·International Journal of Surgery·Francisco J García-MolinaIosvany Rivero-Henández
May 6, 2015·Surgical Oncology·T BuchbjergM B Mortensen
Jun 26, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Thomas AparicioPauline Afchain
May 28, 2013·International Journal of Surgery Case Reports·Toru NakanoNoriaki Ohuchi
Jan 18, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·D DorcarattoE Hoti
Mar 30, 2016·World Journal of Gastrointestinal Surgery·Jordan M CloydBrendan C Visser
Feb 22, 2012·World Journal of Gastrointestinal Surgery·Federico SistaGianfranco Amicucci
Sep 26, 2014·World Journal of Gastroenterology : WJG·Naomi KakushimaHiroyuki Ono
Oct 12, 2014·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·George KokosisAlexander Perez
Jun 28, 2018·Annals of Surgical Oncology·Laura L MeijerGeert Kazemier
May 6, 2020·Annals of Surgical Oncology·Nobuhito NittaKatsuhiko Uesaka
Feb 27, 2007·Journal of Surgical Oncology·Kathryn LanukeLloyd A Mack
Aug 27, 2015·World Journal of Gastroenterology : WJG·Feliciano Chanana PaquissiFrancisco Viamontes Diaz
Sep 26, 2012·International Journal of Molecular Medicine·Jing-Xia ChangGuo-Jun Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.