PMID: 11333845May 3, 2001Paper

Extent of thermal processing of infant formula affects copper status in infant rhesus monkeys

The American Journal of Clinical Nutrition
B LönnerdalE L Lien

Abstract

Infant rhesus monkeys are excellent models in which to study the effect of infant formulas on trace element absorption and status. Infants fed powdered formula from birth exhibit normal growth and have blood variables similar to those of breast-fed infants. The objectives were to evaluate the effects of feeding ready-to-feed (RTF) formulas exposed to different heat treatments to infant monkeys, and, for one of these formulas, to compare the effect of fortification with 2 iron concentrations. From birth to age 5 mo, infant monkeys (n = 6/group) were fed one of the following formulas exclusively: 1) 12 mg Fe/L processed in cans (RTF-12), 2) formula in glass bottles with 12 mg Fe/L and manufactured by an ultrahigh-temperature (UHT) process (UHT-12), or 3) formula manufactured by a standard thermal process (STP), containing either 8 (STP-8) or 12 (STP-12) mg Fe/L. All formulas had similar copper concentrations (0.6 mg Cu/L). Anthropometric measures and venous blood samples were taken monthly. Weight and length gain did not differ among groups; however, the STP-12 group weighed less than the UHT-12 group at ages 2, 4, and 5 mo. Hemoglobin values were significantly lower in the RTF-12 group than in all other groups at ages 4 and 5 mo...Continue Reading

References

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Citations

Sep 28, 2004·Journal of Pediatric Gastroenterology and Nutrition·Carlo AgostoniUNKNOWN ESPGHAN Committee on Nutrition
Oct 9, 2002·The Journal of Nutrition·Joseph R Prohaska, Bruce Brokate
Nov 1, 2007·Journal of Food Protection·M C Pina PérezA Martínez López
Jun 7, 2008·The Journal of International Medical Research·M GiovanniniC Agostoni
Sep 26, 2003·Journal of Pediatric Gastroenterology and Nutrition·Magdalena ArayaRicardo Uauy
Nov 20, 2002·Pediatric Research·Talkad S RaghuveerJohn A Widness
Nov 9, 2005·Annals of Nutrition & Metabolism·Beatriz Sarriá, M Pilar Vaquero
Jun 16, 2012·Annals of Nutrition & Metabolism·Bo Lönnerdal
Jul 22, 2004·Journal of Agricultural and Food Chemistry·E PeñaP Bermejo

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