Abstract
To assess the outcome of patients treated with radical radiotherapy for cervical cancer who received an external beam boost, in place of intracavitary brachytherapy (ICT), after irradiation to the whole pelvis. Case notes were reviewed for all patients treated in this way in a single center between 1996 and 2004. Patient and tumor details, the reasons why ICT was not possible, and treatment outcome were documented. Forty-four patients were identified. The mean age was 56.4 years (range, 26-88 years). Clinical International Federation of Gynecology and Obstetrics or radiologic stage for Stages I, II, III, and IV, respectively, was 16%, 48%, 27%, and 7%. A total radiation dose of 54-70 Gy was given (75% received > or =60 Gy). Reasons for ICT not being performed were technical limitations in 73%, comorbidity or isolation limitations in 23%, and patient choice in 4%. The median follow-up was 2.3 years. Recurrent disease was seen in 48%, with a median time to recurrence of 2.3 years. Central recurrence was seen in 16 of the 21 patients with recurrent disease. The 5-year overall survival rate was 49.3%. The 3-year cancer-specific survival rate by stage was 100%, 70%, and 42% for Stages I, II, and III, respectively. Late Grades 1 and ...Continue Reading
References
Dec 1, 1992·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A FylesJ Simm
Feb 1, 1989·International Journal of Radiation Oncology, Biology, Physics·Z Z Lei, F Z He
Mar 15, 1988·Cancer·G E RoldanD C McIlrath
Sep 1, 1986·International Journal of Radiation Oncology, Biology, Physics·Y AkineK Ohmi
Sep 15, 1985·Cancer·W S YuG A King
Apr 1, 1970·Radiology·J R CastroG H Fletcher
May 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A W FylesG A Rawlings
Nov 1, 1995·International Journal of Radiation Oncology, Biology, Physics·H M SandlerA Lichter
Feb 15, 1993·International Journal of Radiation Oncology, Biology, Physics·R M LancianoG E Hanks
Mar 31, 1999·International Journal of Radiation Oncology, Biology, Physics·M D Logsdon, P J Eifel
Feb 24, 2001·Clinical Oncology : a Journal of the Royal College of Radiologists·A S DentonUNKNOWN UK Link Gynaecology-Oncology Group
Sep 21, 2001·Lancet·J A GreenC J Williams
Dec 14, 2004·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ludvig Paul MurenOlav Dahl
Jan 13, 2006·Gynecologic Oncology·Gilles HouvenaeghelLaurence Gonzague-Casabianca
Feb 16, 2006·Clinical Oncology : a Journal of the Royal College of Radiologists·E P SaibishkumarI Mallick
Mar 1, 2006·Gynecologic Oncology·J M ClasseUNKNOWN Groupe des Chirurgiens de Centre de Lutte Contre le Cancer
Aug 8, 2006·Gynecologic Oncology·K MatsuuraK Ito
Citations
Aug 15, 2013·Current Opinion in Oncology·Charles A Kunos, Ming Spelic
Feb 7, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Philip E SchanerRobert Y Kim
Nov 26, 2010·BMC Cancer·Chen-Hsi HsiehPei-Wei Shueng
Feb 18, 2009·World Journal of Surgical Oncology·Lucely CetinaAlfonso Dueñas-González
May 4, 2013·Radiation Oncology·Simone MarnitzMarkus Kufeld
Jan 5, 2013·Radiation Oncology·Fernanda G HerreraMahmut Ozsahin
Sep 4, 2013·BioMed Research International·Gregory J KubicekTamara LaCouture
Mar 5, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Oliver NeumannSimone Marnitz
Jan 27, 2016·Brachytherapy·Karine A Al Feghali, Mohamed A Elshaikh
Oct 4, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ericka WiebeGillian Thomas
Jun 12, 2010·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Benjamin T GieldaKatherine L Griem
Mar 12, 2010·Seminars in Radiation Oncology·Kari TanderupJacob C Lindegaard
Sep 14, 2014·International Journal of Radiation Oncology, Biology, Physics·Beant S GillSushil Beriwal
Oct 5, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Adriana BermudezEric Leung
Oct 15, 2013·International Journal of Radiation Oncology, Biology, Physics·Alessandro ClivioSimone Marnitz
Aug 10, 2010·Clinical Oncology : a Journal of the Royal College of Radiologists·M A Zahra
Apr 17, 2015·BMC Cancer·Xin WangFeng Xu
Mar 8, 2013·Brachytherapy·Daya Nand SharmaPramod Kumar Julka
Sep 11, 2014·Journal of Applied Clinical Medical Physics·Caitlin MerrowMatthew B Podgorsak
Jul 13, 2016·Technology in Cancer Research & Treatment·Rosario MazzolaFilippo Alongi
Jul 26, 2018·Medicine·Ines VendrellLuís Costa
Dec 1, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Haeyoung KimSei Kyung Chang
Sep 25, 2020·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Janis MorgenthalerSimone Marnitz
Oct 1, 2017·International Journal of Particle Therapy·Manoj K SharmaSwarupa Mitra
Mar 20, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Roberta LazzariBarbara Alicja Jereczek-Fossa
Dec 12, 2018·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Ana M Tornero-López, Damián Guirado
Dec 12, 2018·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Loreto YanezHugo Marsiglia
Feb 27, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maura CampitelliCynthia Aristei
Jul 20, 2021·Curēus·Christopher JohnSatish S Kondaveeti
Aug 14, 2021·Radiation Oncology·Tae Hoon LeeKeun-Yong Eom