Abstract
Evaluation of bladder-preserving treatment protocol. To evaluate the long-term results of iridium-192 brachytherapy-based bladder-sparing treatment strategy in patients with solitary invasive bladder tumours. We performed a retrospective analysis of 111 patients with solitary T1G3-T2Gall bladder tumours (< or = 5 cm), who were treated with iridium-afterloading brachytherapy between February 1988 and May 2007. After transurethral tumour resection, external beam radiotherapy (28 Gy; 12 fractions) was given, followed by brachytherapy (Iridium-192; 40 Gy). Partial cystectomy was part of the treatment strategy in nine patients. In five of those patients a T3 tumour was found, and they were included in the analysis. The 5-, 10- and 15-yr overall survival rate (OS); disease-specific survival rate (DSS); and disease-free survival rate (DFS) estimates were determined using the Kaplan-Meier method. Mean follow-up period was 6.2 yr (range: 0.2-16.3 yr). At the last follow-up 75 patients were alive without evidence of disease, whereas 17 patients had died without evidence of disease. Nineteen patients died of bladder cancer after a mean follow-up period of 2.9 yr (range: 0.5-9.0). OS rates at 5 yr, 10 yr, and 15 yr were 70%, 55%, and 51%, ...Continue Reading
References
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·R RozanJ Douchez
Jan 1, 1991·International Journal of Radiation Oncology, Biology, Physics·D J Brenner, E J Hall
Feb 1, 1996·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M PernotE Luporsi
Dec 10, 1997·International Journal of Radiation Oncology, Biology, Physics·A WijnmaalenW L van Putten
Jul 20, 1999·The Journal of Urology·J E Montie
Oct 6, 2000·Urology·M R Feneley, M Schoenberg
Jun 14, 2002·International Journal of Radiation Oncology, Biology, Physics·Elzbieta M Van der Steen-BanasikJan Willem Leer
Jun 21, 2002·European Urology·Jürgen E GschwendWilliam R Fair
Feb 26, 2003·European Urology·R ChahalS C W Harrison
Apr 23, 2003·European Urology·E SolsonaJ L Monrós
Jun 20, 2003·European Urology·M KuczykUNKNOWN European Society for Oncological Urology
Sep 8, 2004·Urology·Luc GeorgeNaji Salem
Feb 15, 2005·International Journal of Radiation Oncology, Biology, Physics·Floris PosHarry Bartelink
Mar 15, 2005·Acta Oncologica·Lars FokdalHans von der Maase
Jun 9, 2005·European Urology·UNKNOWN Advanced Bladder Cancer (ABC) Meta-analysis Collaboration
Jul 12, 2005·European Urology·J A NieuwenhuijzenS Horenblas
Jan 25, 2006·BJU International·John P SteinDonald G Skinner
Dec 13, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Claus RödelRolf Sauer
Apr 20, 2007·International Journal of Clinical Oncology·Yohei HorikawaTomonori Habuchi
Nov 13, 2007·The Journal of Urology·Ofer N GofritArieh L Shalhav
Dec 13, 2007·European Urology·Renzo Colombo
Citations
Aug 24, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·É RégnierJ-L Lagrange
Jun 22, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C C E KoningB R Pieters
Jul 27, 2010·Current Opinion in Urology·Sanjeev Kotwal, Nicholas Munro
Jan 15, 2014·International Journal of Radiation Oncology, Biology, Physics·Shafak AluwiniArendjan Wijnmaalen
Apr 1, 2010·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Tanja LangsenlehnerKarin S Kapp
Nov 13, 2012·The Journal of Urology·B R PietersS Horenblas
Jul 6, 2012·International Journal of Radiation Oncology, Biology, Physics·Benjamin GoldsmithJohn Christodouleas
Aug 30, 2008·European Urology·Harry W Herr
Aug 30, 2008·European Urology·Luigi Da Pozzo
Jan 5, 2017·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bradley R PietersErik Van Limbergen
Nov 6, 2009·Nature Reviews. Urology·Elie AntebiMark S Soloway
Jan 20, 2017·Radiation Oncology·Marco KrengliCarlo Terrone
Apr 14, 2021·Urologic Oncology·Rodrigo Rodrigues PessoaSimon P Kim
Nov 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C C E KoningB R Pieters