Abstract
To validate a sight-threatening diabetic retinopathy (STDR) risk assessment model to adjust the frequency of eye-screening visits in patients with diabetes mellitus. Retrospective follow-up study of patients with diabetes mellitus attending a diabetes center. Anonimyzed data on gender, type and duration of diabetes, HbA1c, blood pressure and the presence and grade of diabetic retinopathy were gathered to estimate risk for STDR for each individual's worse eye over time by means of a prediction model. Receiver operating characteristics (ROC) analysis was performed to determine the diagnostic ability of the model, and a calibration graph was done to see the model fit. 508 screening intervals were analyzed, median diabetes duration was 10years, 87% were type 2 diabetes mellitus, and 3.1% developed STDR before the next screening visit. The area under the ROC curve was 0.74, and the calibration graph showed that model had a good fit. The reduction in screening frequency was 40% compared with fixed annual screening. Current prediction model used to estimate the risk of developing STDR in patients with diabetes performed well. A personalized screening frequency for diabetic retinopathy could be implemented in practice.
References
Apr 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association
Apr 1, 1982·Radiology·J A Hanley, B J McNeil
Feb 24, 2000·JAMA : the Journal of the American Medical Association·S VijanR A Hayward
Apr 6, 2001·Diabetes Care·J I MaloneUNKNOWN Diabetic Control and Complications Trial
Jun 27, 2002·The British Journal of Ophthalmology·I Kocur, S Resnikoff
Jan 28, 2003·Lancet·Naveed YounisUNKNOWN Liverpool Diabetic Eye Study
Sep 18, 2003·Ophthalmology·C P WilkinsonUNKNOWN Global Diabetic Retinopathy Project Group
Mar 11, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·A WilsonG Grimshaw
Nov 10, 2004·Archives of Ophthalmology·David R MatthewsUNKNOWN UK Prospective Diabetes Study Group
Jul 14, 2007·The British Journal of Ophthalmology·E Olafsdóttir, E Stefánsson
Apr 14, 2010·Acta Ophthalmologica·Jesper MehlsenToke Bek
May 13, 2011·Diabetes Care·Elisabet Agardh, Poya Tababat-Khani
Jul 28, 2011·Diabetologia·T AspelundE Stefánsson
May 9, 2012·Diabetes Care·Daniel ChalkKen Stein
Jul 25, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·G P Leese
Nov 15, 2012·Diabetes Care·Irene M StrattonPeter H Scanlon
May 22, 2013·Diabetologia·H C LookerUNKNOWN Scottish Diabetes Research Network (SDRN) Epidemiology Group and the Scottish Diabetic Retinopathy Collaborative
Jul 4, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·J B Echouffo-TcheuguiK M Narayan
Mar 22, 2014·BMC Medical Research Methodology·Gary S CollinsDouglas G Altman
Apr 26, 2014·Diabetologia·Amber A W A van der HeijdenGiel Nijpels
Citations
Sep 18, 2015·The British Journal of Ophthalmology·S H LundE Stefánsson
Jun 29, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·F ZiemssenH Agostini
Nov 27, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·S Sivaprasad, E Pearce
Apr 5, 2020·Diabetologia·Amber A van der HeijdenJoline W Beulens
Aug 1, 2020·Diabetologia·Sajad EmamipourTalitha L Feenstra
Mar 28, 2020·Acta Ophthalmologica·Svein EstilEinar Stefánsson
Jan 18, 2019·Eye·Sajjad HaiderKrishnarajah Nirantharakumar
Apr 28, 2021·The British Journal of Ophthalmology·John J SmithNoemi Lois
Aug 5, 2021·Investigative Ophthalmology & Visual Science·Xiao-Wen HouChen-Wei Pan
Nov 3, 2021·Systematic Reviews·Sigit Ari SaputroAmmarin Thakkinstian