Extra-nodal T lymphomas of the nasal cavities and sinuses

Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Société d'oto-laryngologie des hôpitaux de Paris
S MestiriS Korbi

Abstract

Extra-nodal T lymphomas of the ear, nose, and throat (ENT) are unusual in Western countries, with differential diagnosis from other destructive and necrotizing lesions of the sino-nasal tract often difficult. Eleven cases of extra-nodal lymphomas of the upper aerodigestive tract tract managed in the ENT department of F. Hached hospital in Sousse, Tunisia, were retrieved over a 10-year period (1995-2004). The aim of our study was to report the clinical and pathological data and the outcome for each patient. The median age of patients was 41-years. The most frequent site of involvement was the nasal cavity. Clinically, the symptoms were not specific. Histological examination identified two cases of T/NK lymphoma and nine cases of T-lymphoma not otherwise specified. Immunohistochemistry and in situ hybridization techniques positively detected Epstein-Barr virus in tumoral cells, in seven cases. Tumor staging, in 10 patients, found distant metastasis in three. Nine patients underwent the following treatment: exclusive radiotherapy (one patient), radiochemotherapy (three patients), and exclusive polychemotherapy (five patients). The two remaining patients had no treatment because of a rapidly unfavorable progression. After a median ...Continue Reading

Citations

Mar 15, 2016·Revue de stomatologie, de chirurgie maxillo-faciale et de chirurgie orale·K DohG Woto-Gaye
Jan 1, 2013·European Annals of Otorhinolaryngology, Head and Neck Diseases·M HmidiA Messary
May 7, 2020·Journal of the Egyptian National Cancer Institute·Nabiha MissaouiSihem Hmissa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Adhesion Molecules in the Brain

Cell adhesion molecules found on cell surface help cells bind with other cells or the extracellular matrix to maintain structure and function. Here is the latest research on their role in the brain.

Related Papers

Annals of Oncology : Official Journal of the European Society for Medical Oncology
L PaganoIntergruppo Italiano Linfomi
Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India
Deviprasad ShettyN A Mohammad
© 2022 Meta ULC. All rights reserved