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Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

Molecular Neurodegeneration

Mar 8, 2011

Ayumi TakamuraEtsuro Matsubara

Abstract

Several lines of evidence indicate that memory loss represents a synaptic failure caused by soluble amyloid β (Aβ) oligomers. However, the pathological relevance of Aβ oligomers (AβOs) as the trigger of synaptic or neuronal degeneration, and the possible mechanism underlying the neuroto...read more

Mentioned in this Paper

Hippocampus (Brain)
Histocytochemistry
MICA gene
SYP gene
Hybridomas
Cytotoxicity Assay
Immunoblotting
Immunohistochemistry
Assay
Adherence (Attribute)
Paper Details
References
  • References32
  • Citations13
1234
  • References32
  • Citations13
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Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse

Molecular Neurodegeneration

Mar 8, 2011

Ayumi TakamuraEtsuro Matsubara

PMID: 21375782

DOI: 10.1186/1750-1326-6-20

Abstract

Several lines of evidence indicate that memory loss represents a synaptic failure caused by soluble amyloid β (Aβ) oligomers. However, the pathological relevance of Aβ oligomers (AβOs) as the trigger of synaptic or neuronal degeneration, and the possible mechanism underlying the neuroto...read more

Mentioned in this Paper

Hippocampus (Brain)
Histocytochemistry
MICA gene
SYP gene
Hybridomas
Cytotoxicity Assay
Immunoblotting
Immunohistochemistry
Assay
Adherence (Attribute)

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References32
  • Citations13
1234
  • References32
  • Citations13
12
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