Extracellular respiration of dimethyl sulfoxide by Shewanella oneidensis strain MR-1

Proceedings of the National Academy of Sciences of the United States of America
Jeffrey A GralnickDianne K Newman

Abstract

Shewanella species are renowned for their respiratory versatility, including their ability to respire poorly soluble substrates by using enzymatic machinery that is localized to the outside of the cell. The ability to engage in "extracellular respiration" to date has focused primarily on respiration of minerals. Here, we identify two gene clusters in Shewanella oneidensis strain MR-1 that each contain homologs of genes required for metal reduction and genes that are predicted to encode dimethyl sulfoxide (DMSO) reductase subunits. Molecular and genetic analyses of these clusters indicate that one (SO1427-SO1432) is required for anaerobic respiration of DMSO. We show that DMSO respiration is an extracellular respiratory process through the analysis of mutants defective in type II secretion, which is required for transporting proteins to the outer membrane in Shewanella. Moreover, immunogold labeling of DMSO reductase subunits reveals that they reside on the outer leaflet of the outer membrane under anaerobic conditions. The extracellular localization of the DMSO reductase in S. oneidensis suggests these organisms may perceive DMSO in the environment as an insoluble compound.

References

Oct 1, 1990·International Journal of Systematic Bacteriology·U SimiduM Yotsu
Jan 1, 1972·Annual Review of Pharmacology·N A David
Dec 28, 1968·Nature·D H Rasmussen, A P MacKenzie
Jul 1, 1980·The Histochemical Journal·K T Tokuyasu
Mar 1, 1994·The Journal of Applied Bacteriology·C R Myers, J M Myers
Apr 3, 1999·FEMS Microbiology Reviews·R HilleW Reichenbecher
May 13, 1999·International Journal of Systematic Bacteriology·K VenkateswaranK H Nealson
Apr 20, 2001·Molecular Microbiology·M Sandkvist
Mar 2, 2002·Journal of Bacteriology·J Bruce H ShyuDianne K Newman
Apr 4, 2002·Molecular Microbiology·Nicola R StanleyBen C Berks
Jul 19, 2002·Nature·W SundaS Huntsman
Aug 27, 2003·Proceedings of the National Academy of Sciences of the United States of America·Chad W Saltikov, Dianne K Newman
Apr 7, 2004·Science·J Craig VenterHamilton O Smith
Mar 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Arash KomeiliDianne K Newman
Oct 16, 2004·Letters in Applied Microbiology·C R Myers, J M Myers
Nov 30, 2004·Research in Microbiology·Philip BronsteinMatthew P DeLisa
Dec 1, 2004·Annual Review of Genetics·Laura R CroalDianne K Newman
Feb 5, 2005·Applied and Environmental Microbiology·Randa AbboudKenneth H Nealson
Apr 22, 2005·Proceedings of the National Academy of Sciences of the United States of America·Marcel M M KuypersMike S M Jetten
May 11, 2005·Molecular Microbiology·Jeffrey A GralnickDianne K Newman

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Citations

Jun 5, 2007·The Journal of Membrane Biology·Milton H Saier
Mar 25, 2010·Journal of Molecular Evolution·Hamsanathan ShruthiKrishnan Sankaran
Jun 26, 2007·Applied Microbiology and Biotechnology·Meiying XuGuoping Sun
Aug 3, 2011·Applied Microbiology and Biotechnology·Pei-Jie CaiHan-Qing Yu
Mar 30, 2013·Research in Microbiology·Arnaud Rondelet, Guy Condemine
Jul 8, 2008·Nature Reviews. Microbiology·James K FredricksonJames M Tiedje
Dec 19, 2009·Proceedings of the National Academy of Sciences of the United States of America·Robert S HartshorneDavid J Richardson
May 2, 2013·Proceedings of the National Academy of Sciences of the United States of America·Diego ArambulaJeff F Miller
Jul 3, 2013·Applied and Environmental Microbiology·Dongru QiuJizhong Zhou
Oct 7, 2008·Applied and Environmental Microbiology·Heidi H HauJeffrey A Gralnick
Apr 2, 2008·Applied and Environmental Microbiology·Margaret F RomineMary S Lipton
Dec 12, 2012·Applied and Environmental Microbiology·M SchicklbergerJ Gescher
Dec 20, 2011·Applied and Environmental Microbiology·Katrin RichterJohannes Gescher
Nov 10, 2009·Journal of Bacteriology·Dan CoursolleJeffrey A Gralnick
Nov 14, 2006·Journal of Bacteriology·Claribel Cruz-GarcíaJames M Tiedje
Mar 8, 2011·Journal of Bacteriology·Carmen D CordovaAlfred M Spormann
Sep 11, 2012·Journal of Bacteriology·Arnaud Rondelet, Guy Condemine
Apr 30, 2013·PloS One·Haiyan ZhangHaichun Gao
Nov 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·David A WiddickTracy Palmer
Aug 22, 2014·Proceedings of the National Academy of Sciences of the United States of America·Sahand PirbadianMohamed Y El-Naggar
Nov 21, 2014·Journal of the Royal Society, Interface·Marian BreuerJulea N Butt
Oct 16, 2015·FEMS Microbiology Reviews·Silke Leimkühler, Chantal Iobbi-Nivol
Dec 9, 2008·Trends in Microbiology·Matthew I HutchingsIain C Sutcliffe
Jun 27, 2009·Molecular Microbiology·Claudine BaraquetCécile Jourlin-Castelli
Jan 26, 2008·Environmental Microbiology·Flavia F EvansStaffan Kjelleberg
Jul 23, 2008·Molecular Microbiology·Yann Ferrandez, Guy Condemine
Jun 22, 2007·Molecular Microbiology·Jeffrey A Gralnick, Dianne K Newman

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