Extracellular Vesicles for Research on Psychiatric Disorders

Schizophrenia Bulletin
Shin-Ichi KanoIndigo V L Rose

Abstract

Extracellular vesicles (EVs) have gained increasing attention as underexplored intercellular communication mechanisms in basic science and as potential diagnostic tools in translational studies, particularly those related to cancers and neurological disorders. This article summarizes accumulated findings in the basic biology of EVs, EV research methodology, and the roles of EVs in brain cell function and dysfunction, as well as emerging EV studies in human brain disorders. Further research on EVs in neurobiology and psychiatry may open the door to a better understanding of intercellular communications in healthy and diseased brains, and the discovery of novel biomarkers and new therapeutic strategies in psychiatric disorders.

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Citations

Aug 20, 2020·Reviews in the Neurosciences·Barbora KonečnáGabriela Repiská
Mar 23, 2021·Schizophrenia Bulletin·Shin-Ichi KanoAkira Sawa

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