Extracellular vesicles: translational challenges and opportunities

Biochemical Society Transactions
Hannah Clemmens, Daniel Lambert

Abstract

Extracellular vesicles (EVs) are a heterogeneous group of small lipid-enclosed structures with myriad roles in physiology and disease. The recent surge of interest in EVs has led to greater understanding of their biology and appreciation of how they might be utilised as diagnostic and therapeutic tools. There remain, however, a number of challenges that must be overcome before EVs may be used routinely in the clinic. In this review we will discuss the translational potential of EVs and the current technologies available to isolate, purify and analyse EVs and their contents.

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Citations

Jan 31, 2020·PloS One·Anton EmelyanovAndrey Konevega
Mar 25, 2020·International Journal of Molecular Sciences·Danilo BucaPaola Lanuti
Oct 23, 2019·Frontiers in Molecular Neuroscience·Wanying LiuJunping Zhang
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Nov 25, 2020·International Journal of Molecular Sciences·Alessandro LucidiMarco Petrillo
Jan 13, 2021·International Journal of Molecular Sciences·Laura PastorDavid Sanz-Rubio
Apr 17, 2021·Scientific Reports·Jun-Kyu KimChang-Won Hong
Jul 3, 2021·Nature Nanotechnology·Inge Katrin HerrmannGregor Fuhrmann
Dec 18, 2021·Journal of Extracellular Vesicles·Yvonne CouchDavid R F Carter

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