PMID: 2093865Dec 1, 1990Paper

Extracorporeal connection of heterologous spleen (ECHS) in the combined intensive therapy of sepsis

Ortopediia travmatologiia i protezirovanie
O Iu KrasovskiĭA I Kandziuba

Abstract

Biohemosorption by means of extracorporeal connection of heterogeneous spleen renders not only powerful detoxic action, but intensive immunomodulation action as well. Swine spleen used for biohemosorption possess high bacterisorptive and immunomodulating potential. The cases of persistent course of disease, development of antibacterial therapy, grave condition of a patient serve as an indication for application of extracoproreal connection of heterogeneous spleen within the complex of intensive therapy. During 1989 in the hospital were treated 9 patients with osteomyelitis and extensive suppurative foci of soft tissues of the locomotor apparatus, complicated by severe sepsis. Those patients were applied to totally II extracorporeal connections of heterogeneous spleen and 8 biohemosorptions by means of heterogeneous spleen sections. In general, intensive therapy with application of extracorporeal connection of heterogeneous spleen was effective enough. All patients with no exception left hospital in satisfactory condition in 28-56 days after the beginning of treatment.

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