Extracorporeal life support as bridge to lung transplantation: a systematic review

Critical Care : the Official Journal of the Critical Care Forum
Davide ChiumelloLorenzo Del Sorbo

Abstract

Patients with acute respiratory failure requiring respiratory support with invasive mechanical ventilation while awaiting lung transplantation are at a high risk of death. Extracorporeal membrane oxygenation (ECMO) has been proposed as an alternative bridging strategy to mechanical ventilation. The aim of this study was to assess the current evidence regarding how the ECMO bridge influences patients' survival and length of hospital stay. We performed a systematic review by searching PubMed, EMBASE and the bibliographies of retrieved articles. Three reviewers independently screened citation titles and abstracts and agreement was reached by consensus. We selected studies enrolling patients who received ECMO with the intention to bridge lung transplant. We included randomized controlled trials (RCTs), case-control studies and case series with ten or more patients. Outcomes of interest included survival and length of hospital stay. Quantitative data summaries were made when feasible. We identified 82 studies, of which 14 were included in the final analysis. All 14 were retrospective studies which enrolled 441 patients in total. Because of the broad heterogeneity among the studies we did not perform a meta-analysis. The mortality ra...Continue Reading

References

Apr 6, 2002·American Journal of Respiratory and Critical Care Medicine·Jean Chastre, Jean-Yves Fagon
Mar 7, 2006·The Journal of Thoracic and Cardiovascular Surgery·Stefan FischerMartin Strueber
Apr 15, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T M EganF L Grover
Jul 5, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Jonathan B OrensUNKNOWN Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation
Jan 11, 2007·Current Opinion in Anaesthesiology·Paul S MylesGlen P Westall
Jan 16, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Clemens AignerWalter Klepetko
Jul 4, 2008·Critical Care Medicine·Peter E MorrisEdward Haponik
Sep 23, 2008·The Annals of Thoracic Surgery·Michael BrooméFolke Nilsson
Jan 10, 2009·Proceedings of the American Thoracic Society·Maryl Kreider, Robert M Kotloff
Jan 31, 2009·Current Opinion in Critical Care·Antonio PesentiNicolò Patroniti
Apr 1, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·J Wytze VermeijdenErik A Verschuuren
Apr 7, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M StrueberS Keshavjee
Sep 2, 2009·Seminars in Cardiothoracic and Vascular Anesthesia·Jeffrey B RileyGregory J Schears
Oct 20, 2009·The Journal of Thoracic and Cardiovascular Surgery·Mark J RussoJoshua R Sonett
Nov 26, 2009·The Journal of Thoracic and Cardiovascular Surgery·David P MasonEugene H Blackstone
Dec 3, 2009·Current Opinion in Critical Care·Martin Strueber
Jul 20, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K M OlssonM M Hoeper
Oct 12, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Pekka HämmäinenGöran Dellgren
Apr 23, 2011·Clinics in Chest Medicine·Maryl KreiderRobert M Kotloff
Jun 28, 2011·American Journal of Respiratory and Critical Care Medicine·Marius M Hoeper, John Granton
Aug 13, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J P SingerH Chen
Aug 30, 2011·The Annals of Thoracic Surgery·Christian A BermudezYoshiya Toyoda
Sep 8, 2011·Current Opinion in Organ Transplantation·Martin Strueber
Sep 20, 2011·The Journal of Thoracic and Cardiovascular Surgery·Jose P GarciaBartley P Griffith
Oct 4, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Jason D ChristieMarshall I Hertz
Jan 24, 2012·American Journal of Respiratory and Critical Care Medicine·Thomas FuehnerGregor Warnecke
Apr 3, 2012·American Journal of Respiratory and Critical Care Medicine·Lorenzo Del SorboShaf Keshavjee
Jul 17, 2012·The Journal of Thoracic and Cardiovascular Surgery·Jeffrey JavidfarMatthew Bacchetta
Aug 14, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Timothy J GeorgeAshish S Shah
Aug 30, 2012·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Alexis E ShafiiSudish C Murthy
Sep 4, 2012·Current Opinion in Organ Transplantation·Jeffrey Javidfar, Matthew Bacchetta
Oct 26, 2012·Interactive Cardiovascular and Thoracic Surgery·Mario NosottiPaolo Tarsia
Dec 29, 2012·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Enrique Diaz-GuzmanJoseph B Zwischenberger
Jan 15, 2013·The Journal of Thoracic and Cardiovascular Surgery·Charles W HoopesJoseph B Zwischenberger
Jan 22, 2013·The Journal of Thoracic and Cardiovascular Surgery·Yoshiya ToyodaChristian Bermudez
Aug 21, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Marion LafargeHervé Mal
Sep 17, 2013·Transplantation Proceedings·M AnileF Venuta

❮ Previous
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Citations

Dec 24, 2015·Pediatric Transplantation·Jessica G Y Luc, Jayan Nagendran
Dec 26, 2015·Current Opinion in Critical Care·Robert H Bartlett, Kristopher B Deatrick
Jun 11, 2015·Best Practice & Research. Clinical Anaesthesiology·Basil W SchaheenJames M Isbell
Oct 25, 2016·The Annals of Thoracic Surgery·Stéphane CollaudWalter Weder
Feb 4, 2016·American Journal of Respiratory and Critical Care Medicine·Don HayesDmitry Tumin
Mar 24, 2018·Critical Care : the Official Journal of the Critical Care Forum·Alessandro MarchioniEnrico Clini
Jul 6, 2016·Medizinische Klinik, Intensivmedizin und Notfallmedizin·T Staudinger
May 10, 2016·F1000Research·Warwick Butt, Graeme MacLaren
Jan 1, 2015·Critical Care : the Official Journal of the Critical Care Forum·Matthew Edward Cove
Jul 26, 2018·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Frank LangerPhilipp M Lepper
Dec 3, 2016·Transplantation·David K C CooperRichard N Pierson
Mar 4, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Dominik J HoechterVera von Dossow
Apr 17, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Jeremiah William Awori HayangaNorihisa Shigemura
Dec 10, 2015·Current Opinion in Critical Care·Darryl Abrams, Daniel Brodie
Jun 14, 2017·American Journal of Respiratory and Critical Care Medicine·Van HoangAmit D Parulekar
Jan 3, 2020·Seminars in Cardiothoracic and Vascular Anesthesia·J W Awori HayangaHeather K Hayanga
Aug 15, 2020·Oxford Medical Case Reports·María D P MartínezTathagat Narula
May 5, 2017·Intensive Care Medicine·Alain CombesLaurent Papazian
Nov 1, 2016·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Bassam RedwanStefan Fischer
Jan 15, 2020·Respiratory Research·Ryoung-Eun KoUNKNOWN Korean Organ Transplantation Registry Study Group
Sep 1, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shameen SalamAbhijit Duggal
Aug 28, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Mustafa VayvadaErdal Tasci
Nov 7, 2015·Current Opinion in Anaesthesiology·Dominik J Hoechter, Vera von Dossow
Dec 3, 2016·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Christopher UllJustyna Swol
Jul 30, 2020·Seminars in Respiratory and Critical Care Medicine·Mark Greer, Tobias Welte
Mar 6, 2021·General Thoracic and Cardiovascular Surgery·Akihiro Ohsumi, Hiroshi Date
Apr 23, 2019·The Annals of Thoracic Surgery·Alison L HalpernMichael J Weyant
May 25, 2021·Seminars in Respiratory and Critical Care Medicine·John W StokesMatthew Bacchetta
Jul 12, 2021·Revista española de anestesiología y reanimación·I ZarragoikoetxeaR Vicente Guillén
Oct 27, 2021·Biometrics·Jiakun JiangWensheng Guo

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