Extracorporeal membrane oxygenation in acute massive pulmonary embolism: a case series and review of the literature

Perfusion
Rasha Al-BawardyChristopher Kabrhel

Abstract

Extracorporeal membrane oxygenation (ECMO) has been used to stabilize patients with massive pulmonary embolism though few reports describe this approach. We describe the presentation, management and outcomes of patients who received ECMO for massive pulmonary embolism (PE) in our pulmonary embolism response team (PERT) registry. We enrolled a consecutive cohort of patients with confirmed PE for whom PERT was activated and selected patients treated with ECMO. We prospectively captured clinical, therapeutic and outcome data at the time of PERT activation and during the follow-up period for up to 365 days. Thirteen patients who had PERT activation with confirmed PE diagnosis have undergone ECMO since the initiation of our PERT program in 2012. The mean age was 49 ± 19 years. Six (46%) patients were female. All the patients had cardiac arrest, either as an initial presentation or in-hospital cardiac arrest after presentation. All the patients exhibited right ventricular (RV) dilation on echocardiogram with RV hypokinesis. Eight (62%) patients received systemic thrombolysis with intravenous tissue plasminogen activator (tPA) and three (23%) patients underwent catheter-directed thrombolysis therapy using the EKOS system (EKOS Corpora...Continue Reading

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Citations

Oct 1, 2019·Current Opinion in Critical Care·Usman A TahirDuane S Pinto
Feb 19, 2019·Perfusion·Benedict KjaergaardBodil Steen Rasmussen
Feb 8, 2019·The European Respiratory Journal·Fabio IusSerghei Cebotari
Nov 30, 2019·European Heart Journal Supplements : Journal of the European Society of Cardiology·Luca ValerioStefano Barco
Jul 12, 2019·Research and Practice in Thrombosis and Haemostasis·Rachel RosovskyChristopher Kabrhel
Jul 30, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Federico SerticChristian Bermudez
Oct 13, 2020·Current Cardiovascular Risk Reports·Connor TiceTaisei Kobayashi
Jun 9, 2020·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Sundeep GulianiJon Marinaro
Dec 31, 2019·Journal of Cardiothoracic and Vascular Anesthesia·Daniel CormicanHarish Ramakrishna
Feb 6, 2021·Journal of Clinical Medicine·Amandine De CharrièreRaphaël Giraud
May 21, 2020·Translational Research : the Journal of Laboratory and Clinical Medicine·Lauren K Stewart, Jeffrey A Kline
Sep 29, 2020·Emergency Medicine Clinics of North America·Samuel Francis, Christopher Kabrhel
Apr 16, 2021·Critical Care Medicine·Nitin Puri, Kimberley Chavez
Jun 5, 2021·Clinical Case Reports·Ji-Yoon KimIl Woo Shin
Jul 12, 2021·Revista española de anestesiología y reanimación·I ZarragoikoetxeaR Vicente Guillén
Aug 6, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Adham N Abou AliEfthymios D Avgerinos
Aug 8, 2021·Journal of Clinical Medicine·Raphaël GiraudKarim Bendjelid
Nov 7, 2021·Journal of Forensic Sciences·Andrew J Layman, Peter T Lin

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Software Mentioned

SAS
PERT
EKOS

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