PMID: 8583325Nov 1, 1995Paper

Extracorporeal membrane oxygenation in the neonate with congenital renal disease and pulmonary hypoplasia

Journal of Pediatric Surgery
R E CaesarV M Reznik

Abstract

Extracorporeal membrane oxygenation (ECMO) is an effective treatment modality for the newborn with refractory hypoxemia. Oligohydramnios can be associated with congenital renal disease (CRD) and can result in respiratory insufficiency from pulmonary hypoplasia, delayed lung maturation, and persistent pulmonary hypertension of the newborn. In this retrospective study, the authors reviewed the outcome of four children with CRD who required ECMO in the neonatal period. Between October 1987 and December 1995, ECMO was used in four newborns with CRD and pulmonary hypoplasia unresponsive to maximal medical management. The causes of CRD were urinary obstruction (2), renal dysplasia (1), and vesicoureteral reflux (1). Neonatal survivors of ECMO with CRD had regular follow-up with a nephrologist, urologist, and pediatrician. Developmental history, assessment of renal function, and a nutritional evaluation were recorded on each visit. The follow-up period ranged from 6 months to 5 years. All patients with CRD were successfully weaned from ECMO. One child died, at 1 month of age, because of renal failure. The estimated glomerular filtration rates in the three survivors were 20, 24, and 60 mL/min/1.73 m2. Growth and development have been d...Continue Reading

References

May 1, 1978·Current Problems in Surgery·R H Bartlett, A B Gazzaniga
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Aug 1, 1981·Archives of Disease in Childhood·J S WigglesworthP Guerrini

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Citations

Jun 9, 2016·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tomoyuki SakaiMasataka Honda
Apr 2, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Aaron WightmanThomas V Brogan

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