Extracorporeal Membrane Oxygenation Support in Severe COVID-19.

The Annals of Thoracic Surgery
Zachary N KonAubrey C Galloway

Abstract

Coronavirus disease 2019 (COVID-19) remains a worldwide pandemic with a high mortality rate among patients requiring mechanical ventilation. The limited data that exist regarding the utility of extracorporeal membrane oxygenation (ECMO) in these critically ill patients show poor overall outcomes. This report describes our institutional practice regarding the application and management of ECMO support for patients with COVID-19 and reports promising early outcomes. All critically ill patients with confirmed COVID-19 evaluated for ECMO support from March 10, 2020, to April 24, 2020, were retrospectively reviewed. Patients were evaluated for ECMO support based on a partial pressure of arterial oxygen/fraction of inspired oxygen ratio of less than 150 mm Hg or pH of less than 7.25 with a partial pressure of arterial carbon dioxide exceeding 60 mm Hg with no life-limiting comorbidities. Patients were cannulated at bedside and were managed with protective lung ventilation, early tracheostomy, bronchoscopies, and proning, as clinically indicated. Among 321 patients intubated for COVID-19, 77 patients (24%) were evaluated for ECMO support, and 27 patients (8.4%) were placed on ECMO. All patients were supported with venovenous ECMO. Cur...Continue Reading

References

Oct 14, 2009·JAMA : the Journal of the American Medical Association·UNKNOWN Australia and New Zealand Extracorporeal Membrane Oxygenation (ANZ ECMO) Influenza InvestigatorsMarc Ziegenfuss
Sep 23, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Elena Spinelli, Robert H Bartlett
May 24, 2018·The New England Journal of Medicine·Alain CombesUNKNOWN EOLIA Trial Group, REVA, and ECMONet
May 3, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Serena ArnoukJohn Papadopoulos
Apr 7, 2020·JAMA : the Journal of the American Medical Association·Giacomo GrasselliUNKNOWN COVID-19 Lombardy ICU Network
Apr 16, 2020·Critical Care : the Official Journal of the Critical Care Forum·Yingchun ZengQiaoyuan Yan
Apr 23, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jeffrey P JacobsMarvin J Slepian
Apr 23, 2020·JAMA : the Journal of the American Medical Association·Safiya RichardsonTheodoros P Zanos
Apr 28, 2020·The Annals of Thoracic Surgery·Luis AngelRobert J Cerfolio

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Citations

Feb 3, 2021·Intensive Care Medicine·Shahzad ShaefiUNKNOWN STOP-COVID Investigators
Feb 13, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Fausto BiancariAntonio Fiore
Jan 10, 2021·The Journal of Thoracic and Cardiovascular Surgery·Emily ShihUNKNOWN Baylor Scott & White ECMO for COVID Group
Mar 10, 2021·The American Journal of Hospice & Palliative Care·Anirudh RaoHunter Groninger
Mar 2, 2021·The Journal of Thoracic and Cardiovascular Surgery·Stephanie H ChangRobert J Cerfolio
Apr 27, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jeffrey P JacobsVinay Badhwar
May 4, 2021·Nursing Administration Quarterly·Mary SaputoLinda Ohler
Jul 3, 2021·Journal of Community Hospital Internal Medicine Perspectives·Dena H TranAvelino C Verceles
Jul 2, 2021·Case Reports in Immunology·Barbara SteinlechnerBernhard Rössler
Jan 25, 2021·The Annals of Thoracic Surgery·Ali TabatabaiRonson J Madathil
Aug 3, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Tyler C LewisNader Moazami
Sep 18, 2021·Scientific Reports·Alina SîrbuCorrado Priami

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Methods Mentioned

BETA
sedation

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