Extract of white button mushroom affects skin healing and angiogenesis

Microscopy Research and Technique
W P LamD T Yew

Abstract

White button mushroom extract was examined in this study on (1) its potential effect on angiogenesis in chorioallantoic culture and (2) its recovering effect on the skin after injury in the ICR mice. Methods used included TUNEL assay on apoptosis, immunohistochemistry for vascular endothelial growth factor (VEGF), proliferative cell nuclear antigen (PCNA), epidermal growth factor (EGF), transforming growth factor β (TGF-β), and immune factor CD4 and western blotting. The results of chorioallantoic culture showed that the mushroom treatment led to significant increase in densities of VEGF sites. In the skin injury, ICR mice model increased EGF, PCNA, and collagen fibers, along with decrease of TUNEL positive apoptotic cells and limited reaction of TGF-β and CD4 indicated that white button mushroom extract appeared to have beneficial effects on skin in regeneration and after injury.

References

Jul 1, 1986·Chemical & Pharmaceutical Bulletin·A MorigiwaN Ikekawa
May 29, 1974·Biochimica Et Biophysica Acta·G Parmentier, H Eyssen
Jan 1, 1982·Acta Radiologica. Oncology·D T YewY W Chan
Jan 1, 1993·Annual Review of Cell Biology·W G Stetler-StevensonL A Liotta
Sep 1, 1996·Molecular Endocrinology·M H Barcellos-Hoff, T A Dix
May 28, 2008·International Journal of Cosmetic Science·K K Lee, J D Choi
Jul 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·Filomena de NigrisClaudio Napoli
May 25, 2011·Biotechnology Advances·Xiaofei XuXuewu Zhang
May 27, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Filipa S ReisIsabel C F R Ferreira
Jul 19, 2011·Journal of the American Academy of Dermatology·Nina ScheibaPeter Helmbold
Aug 23, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S N ChenMadhu G Soni
Sep 1, 2011·Journal of Medicinal Food·Maria MakropoulouNikolas Fokialakis
Sep 20, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Lawrance C ChandraSolo R Kuvibidila
Sep 21, 2011·International Journal of Biological Macromolecules·Anqiang ZhangPeilong Sun
Sep 22, 2011·The Journal of Endocrinology·Stephen C HanleyLawrence Rosenberg

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