Extracting quantitative information from tissue--an industrial perspective

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
Peter Van Osta

Abstract

The focus of this article is to provide an overview of the current technologies for the pharmaceutical and biotech industry. Disease processes express themselves in the functional and structural disturbance of cellular systems. Cells and their metabolites constitute the building blocks of tissues and entire organisms. Studying the spatial and temporal phenotype of disease processes in tissues at the cellular level reveals a multitude of information about the progress and status of a disease. Detailed exploration of tissues by slide-based cytometry is an important source of information about disease processes. Technological and analytical advances allow us to shed a new light on tissues and to come to a better understanding of the complexity of disease processes. Dealing with complex multidimensional datasets from tissue samples requires an advanced approach to image processing and data management. The increase in computing power and the continuing research into imaging algorithms allow us to improve the exploration of the data content of tissues.

References

Apr 6, 1990·Science·W DenkW W Webb
Jan 1, 1990·Cytometry·P DeanJ Mullikin
Jan 1, 1984·Biological cybernetics·J J Koenderink
Jan 10, 1998·The Journal of Pathology·P N Furness
Jul 14, 1998·Nature Medicine·J KononenO P Kallioniemi
Oct 6, 1999·Current Opinion in Structural Biology·M G Gustafsson
Nov 21, 2000·Statistical Methods in Medical Research·P Smyth
Mar 21, 2002·Expert Review of Molecular Diagnostics·C J Best, M R Emmert-Buck
Jul 13, 2002·Cytometry·Attila Tárnok, Andreas O H Gerstner
Sep 26, 2002·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Tokuko HaraguchiYasushi Hiraoka
Dec 17, 2002·Experimental Hematology·Ronald Simon, Guido Sauter
Apr 5, 2003·Science·Jason R SwedlowPeter K Sorger
Apr 22, 2003·Statistics in Medicine·Edward J Wegman
May 8, 2003·Genome Biology·Andres KrieteJ Mark Braughler
Nov 5, 2003·Nature Biotechnology·Stefan W Hell
Apr 28, 2004·Journal of Structural Biology·Alexander EgnerStefan W Hell
May 7, 2004·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Thomas WürflingerAlfred Böcking
Jun 2, 2004·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Andreas O H GerstnerAttila Tárnok
Jun 2, 2004·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Günter K Valet, Heinz Gert Hoeffkes
Sep 8, 2004·Microscopy Research and Technique·Walter A Carrington, Dimitri Lisin
Sep 24, 2004·Combinatorial Chemistry & High Throughput Screening·Till BraunschweigStephen M Hewitt
Sep 28, 2004·Journal of Biomedical Optics·Kai Huang, Robert F Murphy
Oct 7, 2004·Current Opinion in Neurobiology·Stefan W HellStefan Jakobs
Oct 8, 2004·Journal of Biopharmaceutical Statistics·Xueli LiuSteve Horvath
Oct 27, 2004·Toxicologic Pathology·Bruce McCulloughMarc Bonnefoi

❮ Previous
Next ❯

Citations

Mar 28, 2013·Integrative Biology : Quantitative Biosciences From Nano to Macro·Ehsan Ghayoor Karimiani, Philip Day
Jun 30, 2006·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Attila Tárnok

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

© 2021 Meta ULC. All rights reserved