Extraction of a calcium-phospholipid-phosphate complex from bone

Calcified Tissue Research
A L Boskey, A S Posner

Abstract

A calcium-phospholipid-phosphate complex with a constant 1:1 calcium to total phosphate molar ratio is shown to exist in rabbit and calf bone. This complex, which may be involved in the transport and deposition of bone mineral, appears to constitute a significantly greater proportion of the lipids of younger bone than of more mature bone. The comples was isolated by a modified Folch extraction employing ultrasonic disruption of cellular material. Evidence is presented to show that the complex is a natural constituent of bone rather than one created artifactually during extraction.

References

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Citations

Apr 3, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C ReyM J Glimcher
Aug 15, 2013·Calcified Tissue International·Ana Maria S SimãoPietro Ciancaglini
Jan 1, 1983·Metabolic Bone Disease & Related Research·A L Boskey, D M Timchak
Nov 1, 1980·Journal of Dental Research·R E Howell, B Boyan-Salyers
Jun 1, 1989·The Anatomical Record·B D BoyanA Khare
Jul 1, 1983·Calcified Tissue International·A L Boskey, A H Reddi
Jan 1, 1982·Calcified Tissue International·A M Yaari, I M Shapiro
Jul 1, 1982·Calcified Tissue International·A L BoskeyP G Bullough
Jan 1, 1983·Calcified Tissue International·E D Eanes, J L Costa
Jan 1, 1980·Calcified Tissue International·A L Boskey, A S Posner
Mar 1, 1984·Calcified Tissue International·B D Boyan, A L Boskey
Mar 13, 1979·Calcified Tissue International·L J MartinoJ J Taylor
Sep 1, 1988·The American Journal of Anatomy·S C Marks, S N Popoff
Oct 1, 1986·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·C L RaggioA L Boskey
May 1, 1977·Calcified Tissue Research·A L Boskey, A S Posner
Sep 1, 1979·American Journal of Physical Anthropology·M J Schoeninger
Jan 1, 1990·Calcified Tissue International·P Mularchuk, A Boskey
Apr 1, 1992·Calcified Tissue International·D D DeanB D Boyan
Feb 14, 1997·The Journal of Biological Chemistry·L N WuR E Wuthier
May 1, 1993·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·R M Lauder, A D Beynon
Jan 1, 1981·Archives of Oral Biology·A L BoskeyI D Mandel
Jan 1, 1982·Metabolic Bone Disease & Related Research·A L BoskeyA S Posner
Feb 1, 1980·Archives of Biochemistry and Biophysics·A L BoskeyD M Cordella

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