Extramedullary plasmacytoma of the cricoid cartilage progressing to multiple myeloma: A case report

Oncology Letters
Min WangShixi Liu

Abstract

Extramedullary plasmacytoma (EMP) is an uncommon tumor of the plasma cells, and EMP of the cricoid cartilage is extremely rare The present study reports the rare case of a 43-year-old male complaining of hoarseness and dyspnea for over a year. Computed tomography imaging of the neck revealed an occupying lesion in the cricoid cartilage, and a diagnosis of EMP was subsequently confirmed by histopathological evaluation. The patient underwent surgery, but refused radiotherapy against medical advice. One year later, the patient was diagnosed with a recurrence of EMP via pathological examination and underwent a second surgery, however, radiotherapy was refused. After a further two years and four months, the patient presented with lumps in the neck, and was subsequently diagnosed with multiple myeloma. The patient received systematic chemotherapy in the hematology department; the patient's general condition stabilized, and no further anemia, bone pain, infection or other discomfort was experienced. Solitary plasmacytoma of the cricoid cartilage is a rare lesion and compliance with radiotherapy following surgery may provide significant benefit in the treatment of this disease.

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Methods Mentioned

BETA
electrophoresis
biopsy
surgical resection

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