Extranodal marginal zone B-cell lymphoma mimicking meningioma in lateral ventricle: a case report and possible pathogenesis.

Journal of Neuro-oncology
Tae-Young JungKyung-Hwa Lee

Abstract

We report a case of extranodal marginal zone B-cell lymphoma (MZL) mimicking meningioma in a lateral ventricle and suggest its possible pathogenesis. The patient was a 63-year-old male with seizure attack. MRI showed a 3.5x1.7 cm sized homogeneously enhancing mass in the trigon of the right lateral ventricle, possibly arising from the choroid plexus. The provisional diagnosis was meningioma or metastasis. In the surgical findings, the mass was attached to the choroid plexus and totally removed. Pathologic examination revealed a monotonous population of medium-sized mononuclear lymphoma cells associated with meningothelial whorl formation and neoplastic cells which invaded the meningothelial cells. The tumor was immunopositive for CD79a, CD20, CD43 and bcl-2. We suggest that intracranial extranodal marginal zone B-cell lymphomas might mimic meningiomas, because of their relation with the arachnoid cells and that meningothelial cells serve as a substitute for the mucosal surface in intracranial MALT lymphomas.

References

Jan 1, 1997·The American Journal of Surgical Pathology·S KumarE S Jaffe
Oct 23, 2001·Neuropathology : Official Journal of the Japanese Society of Neuropathology·T ItohK Nagashima
Apr 16, 2002·Histopathology·B Maes, C De Wolf-Peeters
Nov 29, 2002·Blood·Emanuele ZuccaUNKNOWN International Extranodal Lymphoma Study Group

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Citations

Jan 4, 2020·QJM : Monthly Journal of the Association of Physicians·J YangJ Xu
Sep 22, 2012·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Tetsuya UebaKoichi Oshima
Sep 10, 2014·The Neuroradiology Journal·Cristina SebastiánJorge Alfaro
Feb 19, 2016·Experimental and Therapeutic Medicine·Jia-Zhen QinYi-Wu Dai
Feb 9, 2012·Neurosurgery·Sebastian A AhmadiSven O Eicker
Aug 12, 2009·Journal of Hematopathology·Sharathkumar BhagavathiWing C Chan

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