Extraovarian nongestational choriocarcinoma in a postmenopausal woman

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
S DilekA Polat

Abstract

Primary extrauterine choriocarcinoma especially in the postmenopausal period is very rare. A 69-year-old woman, complaining of back pain, weakness, and severe fatigue with gross hematuria, was found to have paraovarian pelvic mass and underwent laparotomy. At the operation, a mass located in the right adnexal region, extending to the retroperitoneum and within the normal pathway of germ cell migration, was observed. Other peritoneal surfaces, the uterus, both the ovaries, and fallopian tubes were normal. Total abdominal hysterectomy, bilateral salphingo-oophorectomy, and excision of the right adnexal mass were performed. The histopathological report showed an extrauterine, nongonadal pure choriocarcinoma. As single-agent chemotherapy with methotrexate was ineffective, the patient received multiagent chemotherapy and responded well to the treatment. After 18 months following chemotherapy, the patient was disease free. Extraovarian nongestational choriocarcinoma can be seen within the normal pathway of germ cell migration and responds to chemotherapy-like gestational choriocarcinoma.

References

Jun 1, 1996·Gynecologic Oncology·G MassenkeilH G Bender
Jul 5, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·S WeissA L Kaplan
Dec 12, 2001·Archives of Pathology & Laboratory Medicine·Z LiuJ C Cruz-Caudillo

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Citations

Nov 27, 2010·Journal of Medical Case Reports·Nisarg R DesaiQun Dai
Jan 17, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ashlesha S Udare, Prabath K Mondel
Aug 24, 2011·Korean journal of urology·Tahir KaradenizCağlar Cakır
Feb 19, 2019·Pathology International·Rikiya SanoMitsuru Shiota

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