Extrapolation of cardiac index from analysis of the left ventricular outflow velocities in children: implication of the relationship between aortic size and body surface area

Paediatric Anaesthesia
Eric WodeyC Ecoffey

Abstract

It has recently been reported in critically ill patients that a linear relationship exists between cardiac index (CI) measured with thermodilution and mean aortic blood flow velocity (MAFV). This hypothesis can be validated mathematically only if the aortic area (AA index) indexed to body surface area (BSA) remains constant and if the relationship between aortic diameter (PhiAo) and BSA is nonlinear. However, several other equations have described the relationship between BSA and, respectively, PhiAo and aortic area (AA) in children. The aim of this study was to determine if the relationships calculated between BSA and aortic size in children (without left ventricular outflow tract abnormality) could validate the hypothesis that MAFV and CI are well linked linearly, leading to its use to determine CI. Two hundred and thirty-two measurements performed in 126 children and infants were retrospectively analysed. PhiAo was measured in the long axis view at the annulus using two-dimensional mode echocardiography with a 5-MHz transducer. Various linear and nonlinear relationships between BSA and, respectively, PhiAo, PhiAoindex, AA and AAindex were determined based on a nonlinear regression method with a model as follows: y=a(xc) + b....Continue Reading

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Citations

Jul 16, 2010·Annales Françaises D'anesthèsie Et De Rèanimation·J-M LietJ-M Dejode
Apr 13, 2015·Archives of Cardiovascular Diseases·Pierre-Emmanuel SéguélaJean-Benoit Thambo
Jul 15, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Anna Jarosz-LeszIwona Maruniak-Chudek
Aug 18, 2021·International Journal of Pediatrics & Adolescent Medicine·Ranaa Akkawi El EdelbiStaffan Eksborg

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