Extraskeletal intracranial mesenchymal chondrosarcoma: case report and literature review

The Kaohsiung Journal of Medical Sciences
Jun-Yih ChenJih-Tsun Ho

Abstract

We present the case of a 13-year-old girl with a huge intracranial mesenchymal chondrosarcoma. She had suffered from severe headache, diplopia, intermittent nausea and vomiting for 1 month. Neurologic examination revealed bilateral blurred optic disc margins and abducens paresis. Magnetic resonance imaging demonstrated a giant, heterogeneous, intensely enhancing mass of 7 x 8 x 6 cm, occupying the bilateral frontal and left high parietal regions and based on the anterior cerebral falx. A presumptive diagnosis of aggressive meningioma was made. The patient underwent bicoronal craniotomy and gross total resection of the tumor. Pathologic examination revealed an extraskeletal mesenchymal chondrosarcoma. She was under regular follow-up and remained free of recurrence after surgery. In addition to the current case, we review previously reported cases of extraskeletal intracranial mesenchymal chondrosarcoma and discuss treatment strategies and outcomes.

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Citations

May 28, 2011·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Lisa LinThomas Ng
Jan 3, 2012·Archives of Pathology & Laboratory Medicine·Rachel J ShakkedHoward D Dorfman
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