PMID: 9649023Jul 2, 1998Paper

Extreme right lobar atrophy of the liver: a rare complication of autoimmune hepatitis

Journal of Clinical Gastroenterology
K YoshiuraT Fukazawa

Abstract

Lobar atrophy is a rare morphologic change of the liver. We describe a 73-year-old woman with mild liver dysfunction and history of Sjögren's syndrome who had right hepatic lobar atrophy. Serum biochemistry levels were as follows: albumin, 4.5 g/dl; total bilirubin, 1.0 mg/dl; alanine aminotransferase, 25 international units/l; aspartate aminotransferase, 27 international units/l; alkaline phosphatase, 333 international units/l; and gamma-glutamyl transpeptidase, 332 international units/l. Serological data were as follows: rheumatoid factor, 27.9; anti-nuclear antibody, 1:640; and antismooth muscle antibody, 1:80. Viral markers for hepatitis B were all negative. Anti-hepatitis C virus (anti-c-100) was negative. Portal hypertension developed thereafter, and the patient died of hepatic failure at age 76. Postmortem examination revealed autoimmune hepatitis with moderate fibrosis, portal vein thrombus, and complete obstruction of the right hepatic duct due to hepatolithiasis. Terminal hepatic failure resulted from combination of decreased hepatic volume due to the right lobar atrophy, exacerbation of autoimmune hepatitis in the remnant left hepatic lobe, decreased portal venous blood flow due to thrombosis, portal hypertension, an...Continue Reading

References

Sep 1, 1991·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·L N MohanS D'Cunha
Jan 1, 1991·Gastrointestinal Radiology·M KanematsuH Doi
Jul 1, 1990·World Journal of Surgery·J M Ham
Sep 1, 1989·Endoscopy·M WatanabeY Shimada
Mar 1, 1985·AJR. American Journal of Roentgenology·J L VazquezT L Lawson
Jun 1, 1988·AJR. American Journal of Roentgenology·J G LoriganS Wallace
Sep 1, 1987·Radiology·D R RadinJ M Halls
Jul 1, 1993·The Korean Journal of Internal Medicine·S J LeeS M Park

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Citations

Jun 30, 2012·La Radiologia medica·C GazzeraG Gandini
Jun 5, 2013·The Pan African Medical Journal·Bouomrani SalemBéji Maher

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