Extremely high prevalence of metabolic syndrome manifestations among Arab youth: a call for early intervention

European Journal of Clinical Investigation
Nasser M Al-Daghri

Abstract

Epidemiological studies have suggested an increased prevalence of metabolic syndrome (MS) among adults in the Middle-East. This study aims to determine the prevalence of MS in a large cohort of Saudi children and adolescents. In this cross-sectional observational study, a total of 1231 randomly selected Saudi children and adolescents aged 10-18 years were recruited. Subjects' information was generated from a database of more than 10,000 Saudi citizens from the existing Biomarkers Screening in Riyadh Program (RIYADH Cohort), Saudi Arabia. Anthropometrics included body mass index, blood pressure, as well as waist and hip circumferences. Fasting blood glucose and lipid profile were determined using routine laboratory procedures. The modified definition of ATP-III (NHANES III) was used for the diagnosis of MS. Overall prevalence of complete MS was 9·4% [confidence interval (CI) 7·8-11·0]. Age-adjusted prevalence according to the European standard population is 5·8%. Boys had a comparable MS prevalence with girls [10·3% (CI 8·2-12·4) vs. 8·1% (CI 5·7-10·5), respectively (P = 0·20)]. Low HDL-cholesterol was the most prevalent of all MS risk factors, affecting 86% (CI 85·0-88·6) and hypertriglyceridemia, the second most prevalent, aff...Continue Reading

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Citations

Jan 31, 2012·Metabolic Syndrome and Related Disorders·Mohsen Azimi-NezhadSophie Visvikis-Siest
Dec 20, 2012·Metabolic Syndrome and Related Disorders·Amanda FriendSteve Turner
May 23, 2012·BMC Medical Genetics·Omar S Al-AttasGeorge P Chrousos
Feb 19, 2013·PloS One·Aaesha E MehairiSyed M Shah
Mar 9, 2012·International Journal of General Medicine·Abdulrahman O Musaiger, Hazzaa M Al-Hazzaa
Jan 26, 2016·Metabolic Syndrome and Related Disorders·Harry Robberecht, Nina Hermans
Mar 11, 2016·Diabetology & Metabolic Syndrome·Nasser M Al-DaghriSudhesh Kumar
Sep 1, 2016·Journal of Clinical Lipidology·Nasser M Al-DaghriMajed S Alokail
Nov 3, 2010·European Journal of Clinical Investigation·Kurt Widhalm
Feb 12, 2015·Journal of Clinical Lipidology·Nasser M Al-DaghriMajed S Alokail
Apr 15, 2015·Journal of the Saudi Heart Association·M Al QahtaniH Alshammari
Sep 26, 2013·Annals of Saudi Medicine·Mohammad AlqahtaniThari Alanazi
Aug 9, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Walid SaeedEkram Al-Eryani
Oct 31, 2019·Journal of Primary Care & Community Health·Ekram W Abd El-WahabFahmy Charl

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