Eye Bank Management of Irregular Descemet Stripping Automated Endothelial Keratoplasty Lenticules.

Cornea
Alessandro RuzzaDiego Ponzin

Abstract

To report the management of precut Descemet stripping automated endothelial keratoplasty (DSAEK) lenticules unsuitable for transplantation because of irregular anterior profile after microkeratome cutting. After preparation for DSAEK, 20 tissues were considered unsuitable for transplantation because of nonhomogeneous posterior stromal thickness. To convert them into suitable tissues for surgery, manual stromal delamination was performed by removing the excess stromal layers after the indications obtained through optical coherence tomography. These tissues were further transplanted as ultrathin DSAEK. Nineteen tissues were delaminated successfully. The average reduction in thickness in the center (63 ± 69 μm; P = 0.0101) and periphery (129 ± 39 μm; P < 0.0001) before and after delamination was significantly different. One tissue showed signs of perforation during manual dissection and therefore considered unsuitable for transplantation. Primary graft failure was reported in one case, but it was not correlated with the tissue preparation. No other clinical complications were observed after surgery. Manual delamination of the stroma because of irregular microkeratome cutting is a viable option to obtain a uniform graft thickness r...Continue Reading

References

Sep 18, 2010·Investigative Ophthalmology & Visual Science·Nathaniel E Knox CartwrightJohn Marshall
Mar 20, 2012·The British Journal of Ophthalmology·Paolo RamaGiorgio Paganoni
Jan 1, 2012·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Hind AlkatanAli Khairi
Mar 21, 2017·Journal of Cataract and Refractive Surgery·Vito RomanoStephen B Kaye
Nov 6, 2018·American Journal of Ophthalmology·Olivia S HuangJodhbir S Mehta
Mar 12, 2020·Arquivos brasileiros de oftalmologia·Mehmet Orcun AkdemirSuphi Acar

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