Abstract
In two previous fMRI studies, it was reported that eyes-open and eyes-closed conditions in darkness had differential effects on brain activity, and typical patterns of cortical activity were identified. Without external stimulation, ocular motor and attentional systems were activated when the eyes were open. On the contrary, the visual, somatosensory, vestibular, and auditory systems were activated when the eyes were closed. In this study, we investigated whether cortical areas related to the olfactory and gustatory system are also animated by eye closure without any other external stimulation. In a first fMRI experiment (n = 22), we identified cortical areas including the piriform cortex activated by olfactory stimulation. In a second experiment (n = 12) subjects lying in darkness in the MRI scanner alternately opened and closed their eyes. In accordance to previous studies, we found activation clusters bilaterally in visual, somatosensory, vestibular and auditory cortical areas for the contrast eyes-closed vs. eyes-open. In addition, we were able to show that cortical areas related to the olfactory and gustatory system were also animated by eye closure. These results support the hypothesis that there are two different states ...Continue Reading
References
Nov 26, 1992·Nature·R J ZatorreE Meyer
Jul 1, 1988·Electroencephalography and Clinical Neurophysiology·G Kobal, C Hummel
Jul 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P Jezzard, R S Balaban
Mar 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K J FristonR Turner
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
Apr 5, 2001·Brain Research Bulletin·B MazoyerN Tzourio-Mazoyer
Oct 5, 2001·Nature Reviews. Neuroscience·D A GusnardM E Raichle
Jan 5, 2002·NeuroImage·N Tzourio-MazoyerM Joliot
Apr 24, 2002·Journal of Cognitive Neuroscience·Paul J LaurientiBarry E Stein
Jun 4, 2002·The American Journal of Psychiatry·Brett Silverstein
Jul 26, 2002·Current Opinion in Neurobiology·Ivanka Savic
Jan 22, 2003·Nature Neuroscience·A K AndersonN Sobel
Jun 20, 2003·NeuroImage·R DeichmannR Turner
Jul 26, 2003·NeuroImage·Esther MarxThomas Brandt
Mar 31, 2004·NeuroImage·Esther MarxThomas Brandt
Apr 23, 2004·Journal of Neurophysiology·Dana M SmallDarren Gitelman
Jun 15, 2004·NeuroImage·Barbara Cerf-Ducastel, Claire Murphy
Jul 12, 2005·NeuroImage·A DeutschländerT Brandt
Aug 17, 2005·Neuron·Jess PorterNoam Sobel
Feb 10, 2009·Journal of Neurosurgery·Jennifer LinnIndra Yousry
Citations
Jul 29, 2009·Klinische Neuroradiologie·Rainer KopietzMartin Wiesmann
Nov 26, 2009·Klinische Neuroradiologie·Rainer KopietzMartin Wiesmann
Aug 15, 2008·Chemical Senses·A M KleemannM Wiesmann
May 6, 2011·Fiziologiia cheloveka·Iu A Boĭtsova, S G Dan'ko
Apr 11, 2013·PloS One·Niall W DuncanGeorg Northoff
Sep 12, 2012·Journal of Psychiatry & Neuroscience : JPN·Niall W Duncan, Georg Northoff
Sep 3, 2013·European Archives of Psychiatry and Clinical Neuroscience·Cinto SegalàsCarles Soriano-Mas
Jan 12, 2007·Current Opinion in Neurology·Marianne Dieterich
Nov 26, 2015·NeuroImage. Clinical·K KollndorferV Schöpf
Nov 26, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Francesca MiragliaPaolo Maria Rossini
Nov 17, 2009·Brain Research Reviews·Jessica AlbrechtJohan N Lundström
Sep 22, 2009·Neuroscience Letters·K HüfnerT Brandt
May 29, 2015·NeuroImage·Ju Lynn OngMichael W L Chee
Mar 24, 2009·Physiology & Behavior·A M KleemannM Wiesmann
Feb 13, 2007·Journal of Affective Disorders·Olga PollatosMartin Wiesmann
Apr 3, 2008·Human Brain Mapping·Jessica AlbrechtMartin Wiesmann
Nov 30, 2012·The European Journal of Neuroscience·Adrienn G Varga, Daniel W Wesson
Jun 8, 2010·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Govinda R PoudelPhilip J Bones
Jan 18, 2014·NeuroImage·Pengfei XuYue-jia Luo
Oct 30, 2012·NeuroImage·Janina SeubertJohan N Lundström
Mar 17, 2015·PloS One·Kathrin KollndorferVeronika Schöpf
Jun 14, 2016·NeuroImage·Max SchneiderVictor I Spoormaker
Jul 15, 2016·BMC Neuroscience·Stefan BrodoehlCarsten M Klingner
Dec 2, 2009·Chemical Senses·R ZerneckeM Wiesmann
Jun 6, 2020·Scientific Reports·Víctor CostumeroCésar Ávila
Jan 13, 2021·Cognitive, Affective & Behavioral Neuroscience·Víctor CostumeroCésar Ávila
Apr 28, 2021·International Journal of Audiology·E-Ching Eugena Kok, Bradley McPherson
Aug 11, 2020·NeuroImage·Yihe WengRuiwang Huang
Jun 16, 2021·Scientific Reports·Maria J S GuerreiroBrigitte Röder