Eye disease in sickling disorders

Hematology/oncology Clinics of North America
S Charache

Abstract

When treating patients with sickling disorders, hematologists and oncologists should know those eye lesions that require referral to an ophthalmologist, those that should lead to referral, and those that rarely are associated with decreased vision. Hyphema in any patient whose red cells contain hemoglobin S falls into the first category. Retinal neovascularization (proliferative retinopathy) and its consequence vitreous hemorrhage fall into the second. The comma sign, angioid streaks, and abnormal color vision fall into the third category. The roles of preoperative transfusion and experimental antisickling therapy in treatment and prevention of eye lesions are incompletely defined at present.

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Citations

Dec 23, 1998·Survey of Ophthalmology·P LeeA P Adamis
Feb 28, 2002·European Journal of Haematology·M C CarraroG C Gerli
Jun 19, 2002·European Journal of Haematology·Iheanyi OkpalaIan Abbs
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