Fabricated Elastin

Advanced Healthcare Materials
Giselle C YeoAnthony S Weiss

Abstract

The mechanical stability, elasticity, inherent bioactivity, and self-assembly properties of elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The ability to engineer specific peptide sequences derived from elastin allows the precise control of these physicochemical and organizational characteristics, and further broadens the diversity of elastin-based applications. Elastin and elastin-like peptides can also be modified or blended with other natural or synthetic moieties, including peptides, proteins, polysaccharides, and polymers, to augment existing capabilities or confer additional architectural and biofunctional features to compositionally pure materials. Elastin and elastin-based composites have been subjected to diverse fabrication processes, including heating, electrospinning, wet spinning, solvent casting, freeze-drying, and cross-linking, for the manufacture of particles, fibers, gels, tubes, sheets and films. The resulting materials can be tailored to possess specific strength, elasticity, morphology, topography, porosity, wettability, surface charge, and bioactivity. This extraordinary tunability of elastin-based constructs enables their use in a range of biomedical and tissu...Continue Reading

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Citations

Dec 15, 2015·Advanced Drug Delivery Reviews·Svenja HindererKatja Schenke-Layland
Jan 19, 2016·Current Opinion in Biotechnology·Behnaz Aghaei-Ghareh-BolaghAnthony S Weiss
Feb 26, 2016·Cell and Tissue Research·Meng XuanYan Zhang
Jul 7, 2015·Biomaterials Science·Jazmin OzsvarAnthony S Weiss
May 14, 2016·Nanomedicine·Matti A HiobAnthony S Weiss
Jan 16, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Falko DoberenzThomas Groth
Sep 28, 2018·Frontiers in Bioengineering and Biotechnology·Antonella BandieraMaria Letizia Focarete
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May 17, 2017·Proceedings of the National Academy of Sciences of the United States of America·Sean E ReichheldSimon Sharpe
Feb 21, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Tamagno PesqueiraAnthony S Weiss
Aug 20, 2020·Cardiovascular Engineering and Technology·Francis O ObiweluozorIn Seok Jeong
Jan 18, 2020·Food Science of Animal Resources·Mehdi NadalianSalma Mohamad Yusop
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Nov 21, 2017·ACS Biomaterials Science & Engineering·Giselle C YeoAnthony S Weiss
May 8, 2017·ACS Biomaterials Science & Engineering·David Miranda-Nieves, Elliot L Chaikof
May 8, 2017·ACS Biomaterials Science & Engineering·Matti A HiobAnthony S Weiss
May 8, 2017·ACS Biomaterials Science & Engineering·Lisa D Muiznieks, Fred W Keeley
Apr 11, 2016·ACS Biomaterials Science & Engineering·Giselle C YeoMarcela M M Bilek
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Oct 2, 2021·Nature Biomedical Engineering·Leyu WangXiaozhong Qiu
Nov 10, 2021·Biomacromolecules·Michèle DaiSébastien Lecommandoux

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