Fabrication and biocompatibility investigation of TiO(2) films on the polymer substrates obtained via a novel and versatile route

Colloids and Surfaces. B, Biointerfaces
Junfei OuShengrong Yang

Abstract

Titanium oxide (TiO(2)) films were successfully deposited onto the polymer substrates of polytetrafluoroethylene (PTFE), polyethylene (PE), and polyethylene terephthalate (PET), which were pre-modified with polydopamine coating (polydopamine and its coating are coded as PDA and PDAc, respectively), by a simple liquid phase deposition (LPD) process. The morphology and chemical state of the obtained TiO(2) films were characterized by field emission scanning electron microscope (FE-SEM) and X-ray photoelectron spectroscopy (XPS), respectively. Subsequently, the biocompatibility of the samples was investigated by 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) colorimetric assay and acridine orange staining of MC-3T3 osteoblast cells, and the results demonstrated that the fabricated TiO(2) films could markedly improve the in vitro cytocompatibility. So, the presented route is anticipated to be a promising surface modification methodology to improve the practical outcome of the implanted materials for its versatility and validity.

References

Oct 20, 2007·Science·Haeshin LeePhillip B Messersmith
Oct 1, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Luca GiorgettiPaolo Milani

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Citations

Oct 19, 2012·ACS Applied Materials & Interfaces·Junfei OuWen Li
Aug 5, 2011·Colloids and Surfaces. B, Biointerfaces·Roya Dastjerdi, Majid Montazer
May 3, 2011·Journal of Chromatography. a·Juanjuan FengShengxiang Jiang
Sep 4, 2012·Journal of Biomedical Materials Research. Part a·Dave MangindaanMeng-Jiy Wang
Jul 24, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Xiao Wei TanJodhbir S Mehta
Feb 18, 2012·Journal of Biomedical Materials Research. Part a·Marshal DhayalGopal Pande
Dec 15, 2016·ACS Applied Materials & Interfaces·Andri K RiauJodhbir S Mehta

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