Fabrication, mechanical properties and in vitro degradation behavior of newly developed ZnAg alloys for degradable implant applications

Materials Science & Engineering. C, Materials for Biological Applications
M Sikora-JasinskaMaurizio Vedani

Abstract

Zn and Zn-based alloys have been recognized as highly promising biodegradable materials for orthopedic implants and cardiovascular stents, due to their proved biocompatibility and, more importantly, lower corrosion rates compared to Mg alloys. However, pure Zn has poor mechanical properties. In this study, Ag is used as a promising alloying element to improve the mechanical properties of the Zn matrix as well as its biocompatibility and antibacterial properties. Accordingly, we design three ZnAg alloys with Ag content ranging from 2.5 to 7.0wt% and investigate the influence of the Ag content on mechanical and corrosion behavior of the alloys. The alloys are developed by casting process and homogenized at 410°C for 6h and 12h, followed by hot extrusion at 250°C with extrusion ratio of 14:1. Degradation behavior is assessed by electrochemical and static immersion tests in Hank's modified solution. Microstructural analysis reveals that hot extrusion significantly reduces the grain size of the alloys. Zn-7.0%Ag alloy shows a reasonably equiaxed and considerably refined microstructure with mean grain size of 1.5μm. Tensile tests at room temperature suggest that increasing the Ag content steadily enhances the tensile strength, while ...Continue Reading

Citations

Jul 4, 2019·Advanced Healthcare Materials·Jeffrey Jones D VenezuelaMatthew Simon Dargusch
Jan 30, 2020·Biomaterials Science·Y LiA A Zadpoor
Aug 31, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dayanidhi Krishana Pathak, Pulak Mohan Pandey
Mar 10, 2019·Annals of Biomedical Engineering·Alon KafriEli Aghion
Dec 2, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Pushan GuoZhenlun Song
Nov 2, 2019·Acta Biomaterialia·Y LiA A Zadpoor
Feb 23, 2021·Bioactive Materials·Erlin ZhangGaowu Qin
Mar 13, 2021·Advanced Functional Materials·Irsalan CockerillDonghui Zhu
Jul 28, 2019·Acta Biomaterialia·David Hernández-EscobarHendra Hermawan
Sep 14, 2020·Materials Science & Engineering. C, Materials for Biological Applications·Jin HeDa-Chuan Yin
Jun 16, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Kai ChenYubo Fan
Mar 2, 2021·ACS Applied Bio Materials·Alexander A OliverJeremy Goldman
May 7, 2019·ACS Applied Materials & Interfaces·Roger J GuilloryJeremy Goldman

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