Fabrication of functionalized magnetic microspheres based on monodispersed polystyrene for quantitation of allyl-benzodioxoles coupled with gas chromatography and mass spectrometry

Journal of Chromatography. a
Xiujun CaoGuoxing Song

Abstract

Monodispersed magnetic microspheres were synthesized by the magnetization of the aminized polystyrene cores and the subsequent polymerization of allyl glycidyl ether, divinylbenzene and N-vinyl-2-pyrrolidone, which exhibited excellent monodispersity in aqueous solution and high efficiency for allyl-benzodioxoles extraction. Various techniques, including scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FT-IR) and vibrating sample magnetometry (VSM) were employed to characterize the composites. Coupled with gas chromatography-mass spectrometry (GC-MS), a sensitive and simple magnetic solid phase extraction (MSPE) procedure based on the prepared microspheres was established for determination of allyl-benzodioxoles in cola-flavoured drinks. The factors affecting the extraction procedure, such as pH value, adsorbent amount, adsorption time, desorption solution and desorption time were optimized. The developed method was characterized by a high recovery (spiked at 5 μg L-1, 25 μg L-1 and 250 μg L-1), a low detection limit (0.05 μg L-1 for safrole and 0.08 μg L-1 for myristicin), a good linearity (correlation coefficients higher than 0.9990 for both) and a satisfactor...Continue Reading

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