Fabry's disease presenting as ventricular tachycardia and left ventricular 'hypertrophy'

European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology
Subodh B JoshiAnuradha Aggarwal


Fabry's disease (FD) is a genetic disorder leading to deficiency of alpha-galactosidase A. Enzymatic replacement therapy has recently become available. Patients with classical FD develop multi-system involvement; however, there is an increasingly recognized cardiac variant that presents as unexplained left ventricular hypertrophy. We describe a patient with Fabry's disease who presented with ventricular tachycardia.


Feb 7, 1991·The New England Journal of Medicine·W von ScheidtRobert J Desnick
Aug 16, 1973·The New England Journal of Medicine·C P RoudebushO H Bing
Aug 3, 1995·The New England Journal of Medicine·S NakaoH Sakuraba
Jan 26, 1999·JAMA : the Journal of the American Medical Association·Peter J MeikleW F Carey
May 29, 2000·American Heart Journal·Ales LinhartM Aschermann
Jul 7, 2001·The New England Journal of Medicine·Andrea FrustaciRobert J Desnick
Jul 7, 2001·The New England Journal of Medicine·C M EngInternational Collaborative Fabry Disease Study Group
Mar 27, 2002·Cerebrovascular Diseases·Frank ThömkeHanns Christian Hopf
Apr 2, 2003·Circulation·Maurizio PieroniAndrea Frustaci
Sep 20, 2005·The American Journal of Cardiology·Jaymin S ShahPerry Elliott
Oct 14, 2005·Pacing and Clinical Electrophysiology : PACE·Osamu IgawaIchiro Hisatome
Apr 25, 2006·Journal of the American College of Cardiology·Maurizio PieroniAndrea Frustaci

Related Concepts

Fabry Disease
Differential Diagnosis
2D Echocardiography
Tachycardia, Ventricular
Left Ventricular Hypertrophy
Hereditary Diseases
System, Multi-Hospital
Replacement Therapy
Variant Cardiac Valve

Related Feeds


Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.