Facial cutaneous Rosai-Dorfman disease: A case report and literature review

Experimental and Therapeutic Medicine
Sheng Fang, Ai-Jun Chen

Abstract

Rosai-Dorfman disease (RDD), otherwise known as sinus histiocytosis with massive lymphadenopathy, is a rare disease. Cutaneous RDD (CRDD) is an extremely rare form of RDD, which is limited to the skin. The present study examined a case of purely CRDD in a 25-year-old female patient who presented with a two-month history of red plaques on her face. In addition, a review of the literature was conducted, where the etiology, pathology, clinical characteristics and treatment of the disease were discussed. From a dermatological perspective, the current study aimed to emphasize the histological features and clinical morphology of cutaneous RDD. Clinicians should have sufficient knowledge to be able to recognize and manage this rare condition. The present study found that the presence of reddish-yellow nodules on the face without any particular sensitivity may be useful in the diagnosis of CRDD. Treatment with topical steroids was found to be beneficial in alleviating CRDD.

References

Feb 1, 1978·Archives of Dermatology·H ThaweraniR F Dorfman
Jan 11, 1992·Dermatology : International Journal for Clinical and Investigative Dermatology·D PuppinM Harms
Sep 15, 1998·The American Journal of Pathology·M LuppiG Torelli
Nov 21, 2000·Pediatric Dermatology·J F Silvestre, A Aliaga
Oct 3, 2002·The American Journal of Dermatopathology·Thomas BrennPhillip H McKee
Jun 6, 2003·The British Journal of Dermatology·J-W TjiuT-F Tsai
Nov 18, 2004·Pediatric Blood & Cancer·Sheila Weitzman, Ronald Jaffe
Dec 8, 2004·Journal of the American Academy of Dermatology·Ching-I LuHong-Shang Hong
Apr 19, 2006·Archives of Dermatology·Chih-Chieh Chan, Chia-Yu Chu
Dec 5, 2006·Journal of Clinical Pathology·Y MehraeinE Meese
Jun 20, 2007·Archives of Dermatology·Jochen UtikalDirk Schadendorf
May 20, 2009·Archives of Dermatology·Carl GebhardtRegina Treudler

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Citations

Jul 14, 2018·Journal of Cutaneous Medicine and Surgery·Laura Barona GarcíaSebastian Ortiz-Reina
Jun 23, 2019·Dermatologic Therapy·Mohammad Shahidi-DadrasNasim Ghilizadeh
Mar 19, 2019·Annals of Plastic Surgery·Reem KaramiGhassan Abu Sittah
Sep 4, 2019·Clinical and Experimental Dermatology·S McCarthyL A Murphy
Mar 4, 2017·International Journal of Dermatology·Jinjing JiaYan Zheng
Mar 28, 2021·Photodiagnosis and Photodynamic Therapy·Chan HuXiuli Wang
Aug 26, 2021·Indian Dermatology Online Journal·Neha TanejaSurabhi Vyas

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Methods Mentioned

BETA
biopsy

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