Facial skin rejuvenation by autologous dermal microfat transfer in photoaged patients: Clinical evaluation and skin surface digital profilometry analysis

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
Angelo TrivisonnoGabriele Toietta

Abstract

Cumulative long-term exposure to solar ultraviolet radiation promotes premature skin aging characterized by wrinkle formation and reduced skin elasticity. In this study, we assessed whether microfat transfer could improve dermal and subcutaneous tissue thickness loss associated with photoaging. Twenty-one patients affected by facial photoaging (photodamage grade II-IV; age range 35-62 years; 19 females, 2 males; all of Caucasian origin) were treated using minimally invasive autologous dermal white fat transfer harvested with a recently designed microcannula. The results were determined by clinical assessment and patient self-evaluation and quantified by the Antera 3D(®) dermal digital device for noninvasive, objective, reliable, and accurate assessment of facial skin texture, color, and wrinkle characteristics. Compared with the pretreatment condition, the increment in soft tissue volume and improvement in skin quality and texture were assessed by a dermatologist after treatment. In addition, instrumental evaluation by digital skin profilometry of the treated areas revealed a 41% reduction in average wrinkle depth (7.29 ± 1.04 × 10(-2) mm pretreatment vs. 4.31 ± 1.16 × 10(-2) mm at 90 days posttreatment; p < 0.001), improved sk...Continue Reading

Citations

Mar 21, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Maurizio CavalliniMariagrazia Patalano
Dec 21, 2019·Plastic and Reconstructive Surgery·Anqi HeFazhi Qi
Nov 7, 2019·Plastic and Reconstructive Surgery·Joris A van DongenBerend van der Lei
Oct 17, 2018·Plastic and Reconstructive Surgery. Global Open·Mark J LandauJoel A Aronowitz
Feb 26, 2020·Plastic and Reconstructive Surgery·Anqi HeFazhi Qi
Oct 25, 2020·Stem Cell Research & Therapy·Angelo TrivisonnoGabriele Toietta
Jun 9, 2021·Facial Plastic Surgery : FPS·Fatih IrmakAysim Ozagari
Aug 22, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Fethiye Damla Menkü ÖzdemirFatma Figen Özgür
Aug 24, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Eshant BhatiaRinti Banerjee
Dec 23, 2021·Experimental and Therapeutic Medicine·Maria Ludovica DeottoMauro Alaibac

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