Facile and efficient reduction of ketones in the presence of zinc catalysts modified by phenol ligands

Chemistry, an Asian Journal
Stephan EnthalerMatthias Driess

Abstract

In the present study, the zinc-catalyzed hydrosilylation of various ketones to give their corresponding alcohols has been examined in detail. Diethyl zinc that can be modified by easily accessible phenol ligands allows the efficient reduction of various aryl and alkyl ketones. By using a practical in situ catalyst, excellent turnover frequencies up to 1000 h(-1) and a broad functional group tolerance were achieved.

References

Nov 9, 2002·Organic Letters·Bruce H LipshutzKevin Noson
Jun 24, 2004·Angewandte Chemie·Joel M Hawkins, Timothy J N Watson
Mar 29, 2006·Angewandte Chemie·Sebastian PolarzMatthias Driess
Nov 1, 2007·Chemical Communications : Chem Comm·Marco BandiniAchille Umani-Ronchi
Jan 25, 2008·Acta Crystallographica. Section C, Crystal Structure Communications·Anders Lennartson, Mikael Håkansson

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Citations

Aug 7, 2012·Chemistry, an Asian Journal·Xiao-Feng Wu
Jan 19, 2012·Chemistry : a European Journal·Stephan Enthaler, Maik Weidauer
Dec 17, 2011·Chemistry, an Asian Journal·Kathrin JungeMatthias Beller
Jul 6, 2011·Chemistry : a European Journal·Stephan Enthaler
Oct 1, 2011·Chemistry, an Asian Journal·Stephan Enthaler, Shigeyoshi Inoue
May 28, 2014·Chemistry : a European Journal·Phillip Jochmann, Douglas W Stephan
Nov 12, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·K Revunova, G I Nikonov
Nov 14, 2020·Chemistry : a European Journal·Łukasz MąkolskiJanusz Lewiński
Jun 2, 2021·Organic & Biomolecular Chemistry·Kristina GroutchikRoman Dobrovetsky

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