Facile and highly efficient synthesis of fluorinated heterocycles via Prins cyclization in ionic liquid hydrogen fluoride salts

Chemical Communications : Chem Comm
Yuichiro KishiToshio Fuchigami

Abstract

Prins cyclization of homoallylic alcohols, thiols, and amines with various aldehydes in an ionic liquid HF salt (Et(4)NF.5HF) afforded the corresponding 4-fluorinated heterocycles in excellent yields.

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Citations

May 14, 2009·Chemical Communications : Chem Comm·Shinsuke InagiToshio Fuchigami
Jun 28, 2011·Chemical Communications : Chem Comm·Toshio Fuchigami, Shinsuke Inagi
Aug 1, 2009·Future Medicinal Chemistry·Susan C WilkinsonVéronique Gouverneur
Jul 12, 2017·The Journal of Organic Chemistry·Yunhe LvQian Zhang
Jul 16, 2011·Angewandte Chemie·Tao XuGuosheng Liu
Aug 21, 2013·Chemical Communications : Chem Comm·Tao WuGuosheng Liu
Jun 25, 2016·Beilstein Journal of Organic Chemistry·Oksana S MikhalchenkoNariman F Salakhutdinov
May 27, 2010·Beilstein Journal of Organic Chemistry·Guillaume G LaunayDavid O'Hagan
May 28, 2015·Angewandte Chemie·Gavin Chit TsuiBenjamin List
Sep 18, 2020·Organic & Biomolecular Chemistry·P PadmajaB V Subba Reddy
Aug 16, 2019·Organic Letters·Huai-Ri SunLing Zhou
Sep 17, 2014·Chemical Reviews·Marcos A P MartinsHelio G Bonacorso
Aug 17, 2011·The Journal of Organic Chemistry·B V Subba ReddyRené Grée
Apr 10, 2015·Chemical Reviews·Pier Alexandre ChampagneJean-François Paquin
May 18, 2013·The Journal of Organic Chemistry·B V Subba ReddyB Sridhar

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