PMID: 11311511Apr 20, 2001Paper

Facilitatory effect of substance P on learning and memory in the inhibitory avoidance test for goldfish

Neuroscience Letters
E M SantangeloR Mattioli

Abstract

The aim of this study was to investigate if substance P (SP) can improve learning and memory processes in goldfish, using an inhibitory avoidance test. A two-compartment aquarium with a central sliding door was used. The animals were placed in the white compartment, and after 20 s the door was opened. As they entered the dark compartment, a weight was dropped in front of them. This procedure was repeated three times. After training, the animals were injected intraperitoneally with SP or vehicle. Twenty-four hours after training, the animals were tested and their latency was recorded. The group injected with SP showed an increase in the latency on the test day as compared with the vehicle group. These results suggest SP can facilitate memory in goldfish in an inhibitory avoidance test.

References

Oct 1, 1978·Pharmacology, Biochemistry, and Behavior·R D OlsonG F Michell
Jan 1, 1991·Brain, Behavior and Evolution·G F Striedter, R G Northcutt
Sep 1, 1985·Brain Research Bulletin·W A Banks, A J Kastin
Mar 1, 1986·Behavioral and Neural Biology·K SchlesingerT N Chase
Aug 1, 1986·Pharmacology, Biochemistry, and Behavior·C Tomaz, J P Huston
Jan 1, 1989·The Journal of Comparative Neurology·S C SharmaR Breckwoldt
Jan 1, 1989·Pharmacology, Biochemistry, and Behavior·B T Lett, V L Grant
Apr 1, 1997·Behavioural Brain Research·R MattioliL Vasconcelos
Aug 1, 1998·Science·D Normile
May 9, 2000·Progress in Neuro-psychopharmacology & Biological Psychiatry·C C MedalhaR Mattioli

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Citations

Jul 31, 2013·PloS One·Andrew J MitchellAlan Saghatelian
Apr 15, 2006·The Journal of Comparative Neurology·Radha G Nair-RobertsAlex Kacelnik

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