Facility Type is Associated with Margin Status and Overall Survival of Patients with Resected Intrahepatic Cholangiocarcinoma

Annals of Surgical Oncology
Grace C LeeMotaz Qadan

Abstract

Many studies have demonstrated associations between surgical resections at academic centers and improved outcomes, particularly for complex operations. However, few studies have examined this relationship in intrahepatic cholangiocarcinoma (ICC). The hypothesis of this study was that facility type is associated with improved postoperative outcomes and survival for patients with ICC who undergo resection. Patients with stages 1 to 3 ICC who underwent hepatectomy were identified using the National Cancer Database (NCDB) (2004-2014). Facilities were categorized as academic or community centers per Commission on Cancer designations. High-volume hospitals were those that performed 11 or more hepatectomies per year. Multilevel logistic mixed-effects models to identify predictors of outcomes and parametric survival-time models were used to determine overall survival (OS). The study identified 2256 patients. Of these patients, 423 (18.8%) were treated at community centers, and 1833 (81.3%) were treated at academic centers. Nearly all high-volume centers were academic facilities (98.5% academic vs. 1.5% community centers), whereas low-volume centers were mixed (65.5% academic vs. 34.5% community centers) (p < 0.001). Surgery performed a...Continue Reading

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Citations

May 10, 2020·Journal of Clinical Medicine·Enrico GringeriFrancesco Paolo Russo
Jan 6, 2021·Journal of Clinical Medicine·Eliza W BealTimothy M Pawlik
Feb 4, 2021·Current Problems in Surgery·T Peter KinghamMichael I D'Angelica
Sep 7, 2020·American Journal of Surgery·Julie SiegelWilliam P Lancaster
Sep 6, 2020·The Journal of Craniofacial Surgery·Sara BehbahaniBoris Paskhover
Nov 4, 2021·Expert Review of Anticancer Therapy·D Brock HewittTimothy M Pawlik

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