Factor analysis of medical image sequences improves evaluation of first-pass MR imaging acquisitions for myocardial perfusion

Academic Radiology
M JanierPierre Croisille

Abstract

Factor analysis of medical image sequences (FAMIS) applied to gadolinium chelate-enhanced subsecond magnetic resonance (MR) imaging was evaluated as a postprocessing method for assessing myocardial perfusion in coronary artery disease (CAD). To assess the accuracy of motion correction, five normal volunteers underwent MR imaging at rest. Thirteen patients with well-documented CAD and no myocardial infarction underwent MR imaging at rest and after dipyridamole administration. After motion correction, a single myocardial tissue factor (FAMISt) image was obtained with FAMIS for each raw MR imaging series acquisition. To evaluate how FAMIS could improve the analysis of these acquisitions, five readers visually assessed myocardial perfusion with FAMISt and raw MR images, and a multicase, multireader receiver operating characteristic analysis was performed. FAMISt images significantly improved detection of the perfusion defects when compared with raw MR images (P = .002). Areas under the receiver operating characteristic curves ranged from 0.84 to 0.93 with FAMISt images and from 0.48 to 0.85 with raw MR images. FAMIS applied to first-pass MR imaging series provided myocardial perfusion images that improve the objective assessment of...Continue Reading

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Citations

Sep 13, 2002·NMR in Biomedicine
Apr 30, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Bernhard L GerberDara L Kraitchman
Dec 17, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Taehoon ShinKrishna S Nayak
May 29, 2009·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Pedro FerreiraDavid Firmin
Oct 31, 2006·Academic Radiology·Kevin S Berbaum
Feb 3, 2012·Medical Image Analysis·Vikas GuptaBoudewijn P F Lelieveldt
Nov 25, 2003·Journal of Magnetic Resonance Imaging : JMRI·Thierry DelzescauxMarc Janier
Jan 17, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Alejandro N MazzadiPierre Croisille
Jul 3, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Alejandro N MazzadiPierre Croisille
May 16, 2018·Cardiovascular Engineering and Technology·Narjes BenameurTarek Kraiem
May 31, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Alejandro N MazzadiMarc Janier

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