Factor structure of the Neurological Evaluation Scale in a predominantly African American sample of patients with schizophrenia, unaffected relatives, and non-psychiatric controls

Schizophrenia Research
Michael T ComptonElaine F Walker

Abstract

This study aimed to identify latent factors of the most widely used scale to measure neurological soft signs, the Neurological Evaluation Scale (NES), in a sample of schizophrenia patients, their relatives, and non-psychiatric controls. The NES was administered following the format and instructions of the original scale [Buchanan, R.W., Heinrichs, D.W., 1989. The Neurological Evaluation Scale (NES): a structured instrument for the assessment of neurological signs in schizophrenia. Psychiatry Res. 27, 335-350]. Three factor analyses were conducted using: (1) 23 items of the scale, (2) these 23 items in a sample restricted to African American participants, and (3) 12 items previously recommended based on adequate inter-rater reliability [Sanders, R.D., Forman, S.D., Pierri, J.N., Baker, R.W., Kelley, M.E., van Kammen, D.P., Keshavan, M.S., 1998. Inter-rater reliability of the neurological examination in schizophrenia. Schizophr. Res. 29, 287-292]. Exploratory factor analysis in the overall sample (n = 110) revealed three factors of interest: a "coordination/Romberg" factor (which included the fist-edge-palm test, finger-thumb opposition, rapid alternating movements, and the Romberg test), a "sensory integration" factor (which inc...Continue Reading

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Citations

May 9, 2008·Neuroscience and Biobehavioral Reviews·Raymond C K Chan, Irving I Gottesman
Apr 27, 2007·Schizophrenia Research·Michael T ComptonElaine F Walker
Oct 25, 2016·Acta Neuropsychiatrica·Akin OjagbemiOye Gureje
Dec 1, 2017·Acta Neuropsychiatrica·Konstantinos N FountoulakisIoannis Nimatoudis
Dec 27, 2018·Antioxidants & Redox Signaling·Yeni KimRenata Santos
Aug 9, 2019·Nordic Journal of Psychiatry·Konstantinos N FountoulakisIoannis Nimatoudis
May 1, 2018·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Konstantinos N FountoulakisXenia Gonda
Nov 30, 2021·European Archives of Psychiatry and Clinical Neuroscience·Konstantinos N FountoulakisIoannis Nimatoudis

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