Factors affecting aflatoxin production by Aspergillus parasiticus in a chemically defined medium

Journal of General Microbiology
T V ReddyT A Venkitasubramanian

Abstract

The optimum levels of sucrose, (NH4)2SO4, MgSO4, KH2PO4 and ZnSO4 for aflatoxin production in a chemically defined medium have been established. The last two were found to be essential for fungal growth and aflatoxin production. The effect of various carbon sources on aflatoxin production was tested using the defined medium. Asparagine was found to be essential for aflatoxin production. Very little aflatoxin was produced in the absence of asparagine with any of the other inorganic nitrogen sources tested. Supplementation with yeast extract, Casamino acids, Casitone and peptone increased the aflatoxin yield, but omission of asparagine led to decreased aflatoxin yields even when complex nitrogen sources were present. Asparagine could be replaced by aspartic acid or alanine.

Citations

Jan 3, 2012·Environmental Toxicology and Pharmacology·Starling KalpanaJitendra K Malik
Mar 12, 2004·Annual Review of Phytopathology·G A Payne, M P Brown
Feb 22, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·P B WangikarA G Telang
Dec 2, 2016·Journal of Hazardous Materials·Bin WangShihua Wang
Feb 5, 2020·Frontiers in Microbiology·Rebecca R Sweany, Kenneth E Damann

Related Concepts

Aflatoxins
Quaternary Ammonium Compounds
Asparagine
Aspergillus
Vitreous Carbon
Glucose, (beta-D)-Isomer
Glycerin
Nitrogen
Soil Microbiology
Sucrose

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