Abstract
Aims of this study were to compare serum leptin levels, atherosclerotic markers and carotid intima media thickness (IMT) among the overweight, obese and normal weight healthy adolescents and to investigate the association of carotid IMT with leptin and atherosclerotic markers in adolescence. Seventy obese-overweight adolescents (27 of them obese, 43 of them overweight) and 72 two normal weight adolescents aged 14-18 years were included in this study. Leptin and homocysteine levels and lipid profiles were determined and carotid IMT were measured in all adolescents. Subjects were evaluated as obese-overweight and normal weight and obese, overweight and normal weight. Carotid IMT was significantly different among the overweight adolescents, obese adolescents and the control group (p < 0.001). Leptin levels were significantly higher in obese-overweight adolescents compared to the control group (p < 0.001). Apolipoprotein (Apo) B levels were significantly higher in obese adolescents than the overweight ones and the control group (p < 0.016). There were significantly positive correlations of carotid IMT with leptin, homocysteine and Apo B levels (p < 0.05, r = 0.33, 0.28, 021, respectively). The factors associated with carotid IMT we...Continue Reading
References
Mar 1, 1995·Stroke; a Journal of Cerebral Circulation·G L BurkeG Heiss
Feb 1, 1996·The New England Journal of Medicine·F Rohner-Jeanrenaud, B Jeanrenaud
Aug 1, 1995·International Journal of Epidemiology·E ArnesenJ E Nordrehaug
Nov 1, 1996·The Journal of Clinical Endocrinology and Metabolism·R E OstlundR Gingerich
May 8, 2000·BMJ : British Medical Journal·T J ColeW H Dietz
Jul 6, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·M CicconeG De Pergola
Jan 18, 2002·Nature·Jeffrey Friedman
Aug 30, 2002·Journal of Pediatric Endocrinology & Metabolism : JPEM·Orit FriedlandAlon Eliakim
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Olli T RaitakariJorma S A Viikari
Aug 18, 2004·Pediatrics International : Official Journal of the Japan Pediatric Society·Shilian LiKensuke Harada
Aug 3, 2005·Pediatrics·Gillian S BoydSandra Hassink
Oct 7, 2005·Journal of Hypertension·Weili YanLi Zhang
Dec 6, 2005·Metabolism: Clinical and Experimental·Rosario MartosVíctor Sánchez-Margalet
Dec 14, 2005·European Journal of Pediatrics·Weihua ZhuHenning Neubauer
Apr 11, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·George YuanRobert A Hegele
May 24, 2007·The Journal of Clinical Endocrinology and Metabolism·Véronique BeauloyeSonia M Brichard
Nov 14, 2007·Metabolism: Clinical and Experimental·Rosalinda Posadas-SánchezLiria Yamamoto-Kimura
Feb 21, 2008·Diabetes, Obesity & Metabolism· Anubhuti, Sarika Arora
Apr 25, 2008·Translational Research : the Journal of Laboratory and Clinical Medicine·Tatu A MiettinenJorma Viikari
Citations
Oct 18, 2015·BMC Pediatrics·Min Hae ParkSanjay Kinra
Jun 17, 2016·Medicine·Dan WuHeye Zhang
Mar 25, 2020·Diabetology International·Vignatha SajjaJebaraj Rathinasamy
Apr 2, 2021·International Journal of Clinical Practice·Esra YazarlıBülent Alioğlu